Coronary stent and prolonged dual antiplatelet therapy. A longitudinal study
INTRODUCTIONIn current European guidelines for the management of myocardial infarction after coronary stent placement, there is no consensus on dual antiplatelet therapy (DAPT) ideal duration to prevent stent thrombosis-restenosis without significantly increasing the bleeding risk. OBJECTIVETo repor...
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Veröffentlicht in: | Gaceta médica de México 2022-01, Vol.158 (4), p.216-221 |
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creator | Dámazo-Escobedo, Cristian A Vieyra-Herrera, Gerardo Martínez-Ríos, Marco A García-Navarrete, María G Silva-Ruz, Carlos |
description | INTRODUCTIONIn current European guidelines for the management of myocardial infarction after coronary stent placement, there is no consensus on dual antiplatelet therapy (DAPT) ideal duration to prevent stent thrombosis-restenosis without significantly increasing the bleeding risk. OBJECTIVETo report the percentage of major bleeding and presence of major cardiovascular events associated with prolonged DAPT in patients recruited at the National Institute of Cardiology, treated with primary percutaneous coronary intervention and stent. METHODSA longitudinal, prospective, observational, non-experimental, descriptive study was carried out. Patients were recruited from November 2016 to December 2017. RESULTSOne hundred and thirty-five patients with a mean age of 57 ± 10 years who completed the three-year follow-up were selected. Obesity and hypertension stood out as the main risk factors. After using DAPT for three years, 3.7% of mortality, 1.48% of major bleeding, and 4.4% of thrombosis-restenosis were recorded. CONCLUSIONSProlonged use of DAPT would be justified by the high incidence of thrombosis-restenosis, without a significant increase in bleeding risk, as well as a decrease in major cardiovascular events. |
doi_str_mv | 10.24875/GMM.M22000677 |
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A longitudinal study</title><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Dámazo-Escobedo, Cristian A ; Vieyra-Herrera, Gerardo ; Martínez-Ríos, Marco A ; García-Navarrete, María G ; Silva-Ruz, Carlos</creator><creatorcontrib>Dámazo-Escobedo, Cristian A ; Vieyra-Herrera, Gerardo ; Martínez-Ríos, Marco A ; García-Navarrete, María G ; Silva-Ruz, Carlos</creatorcontrib><description>INTRODUCTIONIn current European guidelines for the management of myocardial infarction after coronary stent placement, there is no consensus on dual antiplatelet therapy (DAPT) ideal duration to prevent stent thrombosis-restenosis without significantly increasing the bleeding risk. OBJECTIVETo report the percentage of major bleeding and presence of major cardiovascular events associated with prolonged DAPT in patients recruited at the National Institute of Cardiology, treated with primary percutaneous coronary intervention and stent. METHODSA longitudinal, prospective, observational, non-experimental, descriptive study was carried out. Patients were recruited from November 2016 to December 2017. RESULTSOne hundred and thirty-five patients with a mean age of 57 ± 10 years who completed the three-year follow-up were selected. Obesity and hypertension stood out as the main risk factors. After using DAPT for three years, 3.7% of mortality, 1.48% of major bleeding, and 4.4% of thrombosis-restenosis were recorded. CONCLUSIONSProlonged use of DAPT would be justified by the high incidence of thrombosis-restenosis, without a significant increase in bleeding risk, as well as a decrease in major cardiovascular events.</description><identifier>ISSN: 0016-3813</identifier><identifier>DOI: 10.24875/GMM.M22000677</identifier><language>eng</language><ispartof>Gaceta médica de México, 2022-01, Vol.158 (4), p.216-221</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1187-fc939318d8f80824c41214306fe18dd0f38351679ad3a3c5dc411a255b19e2b53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27924,27925</link.rule.ids></links><search><creatorcontrib>Dámazo-Escobedo, Cristian A</creatorcontrib><creatorcontrib>Vieyra-Herrera, Gerardo</creatorcontrib><creatorcontrib>Martínez-Ríos, Marco A</creatorcontrib><creatorcontrib>García-Navarrete, María G</creatorcontrib><creatorcontrib>Silva-Ruz, Carlos</creatorcontrib><title>Coronary stent and prolonged dual antiplatelet therapy. A longitudinal study</title><title>Gaceta médica de México</title><description>INTRODUCTIONIn current European guidelines for the management of myocardial infarction after coronary stent placement, there is no consensus on dual antiplatelet therapy (DAPT) ideal duration to prevent stent thrombosis-restenosis without significantly increasing the bleeding risk. OBJECTIVETo report the percentage of major bleeding and presence of major cardiovascular events associated with prolonged DAPT in patients recruited at the National Institute of Cardiology, treated with primary percutaneous coronary intervention and stent. METHODSA longitudinal, prospective, observational, non-experimental, descriptive study was carried out. Patients were recruited from November 2016 to December 2017. RESULTSOne hundred and thirty-five patients with a mean age of 57 ± 10 years who completed the three-year follow-up were selected. Obesity and hypertension stood out as the main risk factors. After using DAPT for three years, 3.7% of mortality, 1.48% of major bleeding, and 4.4% of thrombosis-restenosis were recorded. CONCLUSIONSProlonged use of DAPT would be justified by the high incidence of thrombosis-restenosis, without a significant increase in bleeding risk, as well as a decrease in major cardiovascular events.</description><issn>0016-3813</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNotjzFPwzAQRj2ARCmszB5ZUu7sOLbHKoKClIgF5sqNHQgyToidIf8eIzrd6enpu_sIuUPYsVJJ8XBo213LGABUUl6QDQBWBVfIr8h1jF8ATFSgN6Spx3kMZl5pTC4kaoKl0zz6MXw4S-1ifEZpmLxJzrtE06ebzbTu6J7-OUNa7BCyFPOy3pDL3vjobs9zS96fHt_q56J5PbzU-6boEJUs-k5zzVFZ1StQrOxKZFhyqHqXoYWeKy6wktpYbngnbBbQMCFOqB07Cb4l9_-5-dOfxcV0_B5i57w3wY1LPDKZ25Va5Su_iHVPJw</recordid><startdate>20220101</startdate><enddate>20220101</enddate><creator>Dámazo-Escobedo, Cristian A</creator><creator>Vieyra-Herrera, Gerardo</creator><creator>Martínez-Ríos, Marco A</creator><creator>García-Navarrete, María G</creator><creator>Silva-Ruz, Carlos</creator><scope>7X8</scope></search><sort><creationdate>20220101</creationdate><title>Coronary stent and prolonged dual antiplatelet therapy. A longitudinal study</title><author>Dámazo-Escobedo, Cristian A ; Vieyra-Herrera, Gerardo ; Martínez-Ríos, Marco A ; García-Navarrete, María G ; Silva-Ruz, Carlos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1187-fc939318d8f80824c41214306fe18dd0f38351679ad3a3c5dc411a255b19e2b53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dámazo-Escobedo, Cristian A</creatorcontrib><creatorcontrib>Vieyra-Herrera, Gerardo</creatorcontrib><creatorcontrib>Martínez-Ríos, Marco A</creatorcontrib><creatorcontrib>García-Navarrete, María G</creatorcontrib><creatorcontrib>Silva-Ruz, Carlos</creatorcontrib><collection>MEDLINE - Academic</collection><jtitle>Gaceta médica de México</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dámazo-Escobedo, Cristian A</au><au>Vieyra-Herrera, Gerardo</au><au>Martínez-Ríos, Marco A</au><au>García-Navarrete, María G</au><au>Silva-Ruz, Carlos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coronary stent and prolonged dual antiplatelet therapy. A longitudinal study</atitle><jtitle>Gaceta médica de México</jtitle><date>2022-01-01</date><risdate>2022</risdate><volume>158</volume><issue>4</issue><spage>216</spage><epage>221</epage><pages>216-221</pages><issn>0016-3813</issn><abstract>INTRODUCTIONIn current European guidelines for the management of myocardial infarction after coronary stent placement, there is no consensus on dual antiplatelet therapy (DAPT) ideal duration to prevent stent thrombosis-restenosis without significantly increasing the bleeding risk. OBJECTIVETo report the percentage of major bleeding and presence of major cardiovascular events associated with prolonged DAPT in patients recruited at the National Institute of Cardiology, treated with primary percutaneous coronary intervention and stent. METHODSA longitudinal, prospective, observational, non-experimental, descriptive study was carried out. Patients were recruited from November 2016 to December 2017. RESULTSOne hundred and thirty-five patients with a mean age of 57 ± 10 years who completed the three-year follow-up were selected. Obesity and hypertension stood out as the main risk factors. After using DAPT for three years, 3.7% of mortality, 1.48% of major bleeding, and 4.4% of thrombosis-restenosis were recorded. CONCLUSIONSProlonged use of DAPT would be justified by the high incidence of thrombosis-restenosis, without a significant increase in bleeding risk, as well as a decrease in major cardiovascular events.</abstract><doi>10.24875/GMM.M22000677</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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title | Coronary stent and prolonged dual antiplatelet therapy. A longitudinal study |
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