Swelling‐Mediated Mechanical Stimulation Regulates Differentiation of Adipose‐Derived Mesenchymal Stem Cells for Intervertebral Disc Repair Using Injectable UCST Microgels

Mechanical stimulation is an effective approach for controlling stem cell differentiation in tissue engineering. However, its realization in in vivo tissue repair remains challenging since this type of stimulation can hardly be applied to injectable seeding systems. Here, it is presented that swelli...

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Veröffentlicht in:	Advanced healthcare materials 2023-01, Vol.12 (3), p.e2201925-n/a
Hauptverfasser:	Huang, Xianpeng, Chen, Di, Liang, Chengzhen, Shi, Kesi, Zhou, Xiaopeng, Zhang, Yuang, Li, Yi, Chen, Jiangjie, Xia, Kaishun, Shu, Jiawei, Yang, Biao, Wang, Jingkai, Xu, Haibin, Yu, Chao, Cheng, Feng, Wang, Shaoke, Zhang, Yongxiang, Wang, Chenggui, Ying, Liwei, Li, Hao, Han, Meiling, Li, Fangcai, Tao, Yiqing, Zhao, Qian, Chen, Qixin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylamide Acrylic acid Cell adhesion Cell Differentiation Differentiation (biology) Emulsion polymerization Extracellular matrix Humans injectable upper critical temperature microgels Intervertebral Disc - metabolism Intervertebral Disc Degeneration - metabolism intervertebral disc repairs Intervertebral discs Ion Channels - metabolism mechanical stimulations Mechanical stimuli Mesenchymal Stem Cells Microgels Nucleus pulposus Nucleus Pulposus - metabolism Protein seeding stem cell differentiations Stem cells Stimulation Swelling Tissue engineering
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