Antipsychotics impair regulation of glucose metabolism by central glucose

Hypothalamic detection of elevated circulating glucose triggers suppression of endogenous glucose production (EGP) to maintain glucose homeostasis. Antipsychotics alleviate symptoms associated with schizophrenia but also increase the risk for impaired glucose metabolism. In the current study, we exa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular psychiatry 2022-11, Vol.27 (11), p.4741-4753
Hauptverfasser:	Castellani, Laura N., Pereira, Sandra, Kowalchuk, Chantel, Asgariroozbehani, Roshanak, Singh, Raghunath, Wu, Sally, Hamel, Laurie, Alganem, Khaled, Ryan, William G., Zhang, Xiaolu, Au, Emily, Chintoh, Araba, Remington, Gary, Agarwal, Sri Mahavir, Giacca, Adria, Mccullumsmith, Robert E., Hahn, Margaret K.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase 13 38 38/91 631/378 631/443 64 692/699/476/1799 82/79 Antipsychotic Agents - pharmacology Antipsychotics Behavioral Sciences Benzodiazepines - pharmacology Biological Psychology Chemoreception Gene expression Glucose Glucose - metabolism Haloperidol Homeostasis Hypothalamus Kinases Medicine Medicine & Public Health Mental disorders Metabolism Neurosciences Olanzapine Olanzapine - metabolism Olanzapine - pharmacology Pharmacotherapy Phosphatidylinositol 3-Kinases Protein-serine/threonine kinase Psychiatry Psychotropic drugs Schizophrenia Vascular endothelial growth factor Vascular Endothelial Growth Factor A
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!