Fingerprint multiplex CARS at high speed based on supercontinuum generation in bulk media and deep learning spectral denoising
We introduce a broadband coherent anti-Stokes Raman scattering (CARS) microscope based on a 2-MHz repetition rate ytterbium laser generating 1035-nm high-energy (≈µJ level) femtosecond pulses. These features of the driving laser allow producing broadband red-shifted Stokes pulses, covering the whole...
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| Veröffentlicht in: | Optics express 2022-08, Vol.30 (17), p.30135-30148 |
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| container_title | Optics express |
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| creator | Vernuccio, Federico Bresci, Arianna Talone, Benedetta de la Cadena, Alejandro Ceconello, Chiara Mantero, Stefano Sobacchi, Cristina Vanna, Renzo Cerullo, Giulio Polli, Dario |
| description | We introduce a broadband coherent anti-Stokes Raman scattering (CARS) microscope based on a 2-MHz repetition rate ytterbium laser generating 1035-nm high-energy (≈µJ level) femtosecond pulses. These features of the driving laser allow producing broadband red-shifted Stokes pulses, covering the whole fingerprint region (400–1800 cm −1 ), employing supercontinuum generation in a bulk crystal. Our system reaches state-of-the-art acquisition speed ( |
| doi_str_mv | 10.1364/OE.463032 |
| format | Article |
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| source | DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| title | Fingerprint multiplex CARS at high speed based on supercontinuum generation in bulk media and deep learning spectral denoising |
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