The let-7 microRNA binding site variant in KRAS as a predictive biomarker for head and neck cancer patients with lymph node metastasis

The let-7 family of microRNAs regulate multiple oncogenes including the KRAS gene and has been shown to play a critical role in carcinogenesis. In this study, we aimed to investigate polymorphic alterations of the let-7 miRNA binding site (rs61764370) in the 3′UTR region of the KRAS gene as a predic...

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Veröffentlicht in:	Pathology, research and practice research and practice, 2022-11, Vol.239, p.154147-154147, Article 154147
Hauptverfasser:	Ulusan, Murat, Sen, Sena, Yilmazer, Rasim, Dalay, Nejat, Demokan, Semra
Format:	Artikel
Sprache:	eng
Schlagworte:	head and neck cancer kras polymorphism lcs-6 lymph node metastasis restriction fragment length polymorphism
Online-Zugang:	Volltext
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