Surgical description and outcome of ultrasound‐guided minimally invasive parathyroidectomy in 50 dogs with primary hyperparathyroidism
Objective To describe the surgical technique and clinical outcome of minimally invasive parathyroidectomy for primary hyperparathyroidism (PHPT) in the dog. Animals Fifty client‐owned dogs with PHPT that underwent minimally invasive parathyroidectomy. Study design Retrospective cohort study. Methods...
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Veröffentlicht in: | Veterinary surgery 2023-01, Vol.52 (1), p.18-25 |
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description | Objective
To describe the surgical technique and clinical outcome of minimally invasive parathyroidectomy for primary hyperparathyroidism (PHPT) in the dog.
Animals
Fifty client‐owned dogs with PHPT that underwent minimally invasive parathyroidectomy.
Study design
Retrospective cohort study.
Methods
An ultrasound‐guided mini lateral approach was made via a plane established between the sternocephalicus muscle and sternohyoideus muscles to expose the thyroid gland and enlarged parathyroid gland. Abnormal parathyroid glands were removed en bloc via partial thyroidectomy. The technique for bilateral disease was similar, the skin incision was made on midline and moved laterally to develop the above‐mentioned plane of dissection. Age, sex, breed, bodyweight, ultrasound findings, histopathological diagnosis, surgical time, preoperative clinical signs, and clinical outcome were extracted from the records for descriptive statistics.
Results
A total of 62 glands were surgically removed, including 17 hyperplastic glands (17/62, 27.4%), 34 adenomas (34/62, 54.8%), and two carcinomas (2/62, 3.2%). Hypercalcemia resolved shortly after surgery in 44 dogs (44/45, 97.8%). One dog had recurrent hypercalcemia (1/45, 2.2%), one dog had persistent hypercalcemia (1/45, 2.2%), two dogs had permanent hypocalcemia requiring life‐long calcitriol supplementation (2/45, 4.4%), and one dog died from clinical hypocalcemia (1/45, 2.2%).
Conclusion
Minimally invasive parathyroidectomy was associated with a low morbidity and led to favorable outcomes in 44/45 dogs in this series.
Clinical significance
The results of this study supports the use of minimally invasive parathyroidectomy to treat PHPT in dogs. |
doi_str_mv | 10.1111/vsu.13897 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2724238989</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2758982281</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2787-61397edffa07f586d2247836faaa59f89c617c36ac8aa05f486b5dddead5a0fa3</originalsourceid><addsrcrecordid>eNp10b1u1TAYBmALgeihMHADyBILHdL6J07sEVVQkCp1KEVs0Vf_nOMqiYMdnyobY8deI1eCyzlFCAkvHvz4lT-_CL2m5JiWdbJN-ZhyqdonaEUFZ5US5NtTtCK0oRWvlTpAL1K6IYSouubP0QFvGKNS0RW6u8xx7TX02Niko59mH0YMo8EhzzoMFgeHcz9HSCGP5ueP-3X2xho8-NEP0PcL9uMWkt9aPEGEebPEUICew_BwhAXBJqwTvvXzBk-x3IkL3iyTjX9xn4aX6JmDPtlX-_0QXX388OX0U3V-cfb59P15pVkr26qhXLXWOAekdUI2hrG6lbxxACCUk0o3tNW8AS0BiHC1bK6FMcaCEUAc8EP0bpc7xfA92zR3g0_a9j2MNuTUsZbVrPylVIW-_YfehBzH8rqiRCGMSVrU0U7pGFKK1nX7KTtKuod6ulJP97ueYt_sE_P1YM0f-dhHASc7cOt7u_w_qft6ebWL_AVwaZ8r</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2758982281</pqid></control><display><type>article</type><title>Surgical description and outcome of ultrasound‐guided minimally invasive parathyroidectomy in 50 dogs with primary hyperparathyroidism</title><source>MEDLINE</source><source>Wiley Journals</source><creator>Young, Kenneth M. ; Degner, Daniel A.</creator><creatorcontrib>Young, Kenneth M. ; Degner, Daniel A.</creatorcontrib><description>Objective
To describe the surgical technique and clinical outcome of minimally invasive parathyroidectomy for primary hyperparathyroidism (PHPT) in the dog.
Animals
Fifty client‐owned dogs with PHPT that underwent minimally invasive parathyroidectomy.
Study design
Retrospective cohort study.
Methods
An ultrasound‐guided mini lateral approach was made via a plane established between the sternocephalicus muscle and sternohyoideus muscles to expose the thyroid gland and enlarged parathyroid gland. Abnormal parathyroid glands were removed en bloc via partial thyroidectomy. The technique for bilateral disease was similar, the skin incision was made on midline and moved laterally to develop the above‐mentioned plane of dissection. Age, sex, breed, bodyweight, ultrasound findings, histopathological diagnosis, surgical time, preoperative clinical signs, and clinical outcome were extracted from the records for descriptive statistics.
Results
A total of 62 glands were surgically removed, including 17 hyperplastic glands (17/62, 27.4%), 34 adenomas (34/62, 54.8%), and two carcinomas (2/62, 3.2%). Hypercalcemia resolved shortly after surgery in 44 dogs (44/45, 97.8%). One dog had recurrent hypercalcemia (1/45, 2.2%), one dog had persistent hypercalcemia (1/45, 2.2%), two dogs had permanent hypocalcemia requiring life‐long calcitriol supplementation (2/45, 4.4%), and one dog died from clinical hypocalcemia (1/45, 2.2%).
Conclusion
Minimally invasive parathyroidectomy was associated with a low morbidity and led to favorable outcomes in 44/45 dogs in this series.
Clinical significance
The results of this study supports the use of minimally invasive parathyroidectomy to treat PHPT in dogs.</description><identifier>ISSN: 0161-3499</identifier><identifier>EISSN: 1532-950X</identifier><identifier>DOI: 10.1111/vsu.13897</identifier><identifier>PMID: 36221891</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>25-Hydroxyvitamin D ; Animals ; Calcitriol ; Carcinoma ; Dog Diseases - diagnostic imaging ; Dog Diseases - surgery ; Dogs ; Hypercalcemia ; Hypercalcemia - complications ; Hypercalcemia - surgery ; Hypercalcemia - veterinary ; Hyperparathyroidism ; Hyperparathyroidism, Primary - surgery ; Hyperparathyroidism, Primary - veterinary ; Hypocalcemia ; Hypocalcemia - complications ; Hypocalcemia - surgery ; Hypocalcemia - veterinary ; Invasiveness ; Minimally Invasive Surgical Procedures - methods ; Minimally Invasive Surgical Procedures - veterinary ; Morbidity ; Muscles ; Parathyroid ; Parathyroid gland ; Parathyroid Neoplasms - diagnostic imaging ; Parathyroid Neoplasms - surgery ; Parathyroid Neoplasms - veterinary ; Parathyroidectomy ; Parathyroidectomy - veterinary ; Retrospective Studies ; Skin diseases ; Supplements ; Thyroid ; Thyroid gland ; Thyroidectomy ; Ultrasonic imaging ; Ultrasonic testing ; Ultrasonography, Interventional - veterinary ; Ultrasound</subject><ispartof>Veterinary surgery, 2023-01, Vol.52 (1), p.18-25</ispartof><rights>2022 American College of Veterinary Surgeons.</rights><rights>2023 The American College of Veterinary Surgeons</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2787-61397edffa07f586d2247836faaa59f89c617c36ac8aa05f486b5dddead5a0fa3</cites><orcidid>0000-0002-7855-3751</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fvsu.13897$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fvsu.13897$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36221891$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Young, Kenneth M.</creatorcontrib><creatorcontrib>Degner, Daniel A.</creatorcontrib><title>Surgical description and outcome of ultrasound‐guided minimally invasive parathyroidectomy in 50 dogs with primary hyperparathyroidism</title><title>Veterinary surgery</title><addtitle>Vet Surg</addtitle><description>Objective
To describe the surgical technique and clinical outcome of minimally invasive parathyroidectomy for primary hyperparathyroidism (PHPT) in the dog.
Animals
Fifty client‐owned dogs with PHPT that underwent minimally invasive parathyroidectomy.
Study design
Retrospective cohort study.
Methods
An ultrasound‐guided mini lateral approach was made via a plane established between the sternocephalicus muscle and sternohyoideus muscles to expose the thyroid gland and enlarged parathyroid gland. Abnormal parathyroid glands were removed en bloc via partial thyroidectomy. The technique for bilateral disease was similar, the skin incision was made on midline and moved laterally to develop the above‐mentioned plane of dissection. Age, sex, breed, bodyweight, ultrasound findings, histopathological diagnosis, surgical time, preoperative clinical signs, and clinical outcome were extracted from the records for descriptive statistics.
Results
A total of 62 glands were surgically removed, including 17 hyperplastic glands (17/62, 27.4%), 34 adenomas (34/62, 54.8%), and two carcinomas (2/62, 3.2%). Hypercalcemia resolved shortly after surgery in 44 dogs (44/45, 97.8%). One dog had recurrent hypercalcemia (1/45, 2.2%), one dog had persistent hypercalcemia (1/45, 2.2%), two dogs had permanent hypocalcemia requiring life‐long calcitriol supplementation (2/45, 4.4%), and one dog died from clinical hypocalcemia (1/45, 2.2%).
Conclusion
Minimally invasive parathyroidectomy was associated with a low morbidity and led to favorable outcomes in 44/45 dogs in this series.
Clinical significance
The results of this study supports the use of minimally invasive parathyroidectomy to treat PHPT in dogs.</description><subject>25-Hydroxyvitamin D</subject><subject>Animals</subject><subject>Calcitriol</subject><subject>Carcinoma</subject><subject>Dog Diseases - diagnostic imaging</subject><subject>Dog Diseases - surgery</subject><subject>Dogs</subject><subject>Hypercalcemia</subject><subject>Hypercalcemia - complications</subject><subject>Hypercalcemia - surgery</subject><subject>Hypercalcemia - veterinary</subject><subject>Hyperparathyroidism</subject><subject>Hyperparathyroidism, Primary - surgery</subject><subject>Hyperparathyroidism, Primary - veterinary</subject><subject>Hypocalcemia</subject><subject>Hypocalcemia - complications</subject><subject>Hypocalcemia - surgery</subject><subject>Hypocalcemia - veterinary</subject><subject>Invasiveness</subject><subject>Minimally Invasive Surgical Procedures - methods</subject><subject>Minimally Invasive Surgical Procedures - veterinary</subject><subject>Morbidity</subject><subject>Muscles</subject><subject>Parathyroid</subject><subject>Parathyroid gland</subject><subject>Parathyroid Neoplasms - diagnostic imaging</subject><subject>Parathyroid Neoplasms - surgery</subject><subject>Parathyroid Neoplasms - veterinary</subject><subject>Parathyroidectomy</subject><subject>Parathyroidectomy - veterinary</subject><subject>Retrospective Studies</subject><subject>Skin diseases</subject><subject>Supplements</subject><subject>Thyroid</subject><subject>Thyroid gland</subject><subject>Thyroidectomy</subject><subject>Ultrasonic imaging</subject><subject>Ultrasonic testing</subject><subject>Ultrasonography, Interventional - veterinary</subject><subject>Ultrasound</subject><issn>0161-3499</issn><issn>1532-950X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10b1u1TAYBmALgeihMHADyBILHdL6J07sEVVQkCp1KEVs0Vf_nOMqiYMdnyobY8deI1eCyzlFCAkvHvz4lT-_CL2m5JiWdbJN-ZhyqdonaEUFZ5US5NtTtCK0oRWvlTpAL1K6IYSouubP0QFvGKNS0RW6u8xx7TX02Niko59mH0YMo8EhzzoMFgeHcz9HSCGP5ueP-3X2xho8-NEP0PcL9uMWkt9aPEGEebPEUICew_BwhAXBJqwTvvXzBk-x3IkL3iyTjX9xn4aX6JmDPtlX-_0QXX388OX0U3V-cfb59P15pVkr26qhXLXWOAekdUI2hrG6lbxxACCUk0o3tNW8AS0BiHC1bK6FMcaCEUAc8EP0bpc7xfA92zR3g0_a9j2MNuTUsZbVrPylVIW-_YfehBzH8rqiRCGMSVrU0U7pGFKK1nX7KTtKuod6ulJP97ueYt_sE_P1YM0f-dhHASc7cOt7u_w_qft6ebWL_AVwaZ8r</recordid><startdate>202301</startdate><enddate>202301</enddate><creator>Young, Kenneth M.</creator><creator>Degner, Daniel A.</creator><general>John Wiley & Sons, Inc</general><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7855-3751</orcidid></search><sort><creationdate>202301</creationdate><title>Surgical description and outcome of ultrasound‐guided minimally invasive parathyroidectomy in 50 dogs with primary hyperparathyroidism</title><author>Young, Kenneth M. ; Degner, Daniel A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2787-61397edffa07f586d2247836faaa59f89c617c36ac8aa05f486b5dddead5a0fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>25-Hydroxyvitamin D</topic><topic>Animals</topic><topic>Calcitriol</topic><topic>Carcinoma</topic><topic>Dog Diseases - diagnostic imaging</topic><topic>Dog Diseases - surgery</topic><topic>Dogs</topic><topic>Hypercalcemia</topic><topic>Hypercalcemia - complications</topic><topic>Hypercalcemia - surgery</topic><topic>Hypercalcemia - veterinary</topic><topic>Hyperparathyroidism</topic><topic>Hyperparathyroidism, Primary - surgery</topic><topic>Hyperparathyroidism, Primary - veterinary</topic><topic>Hypocalcemia</topic><topic>Hypocalcemia - complications</topic><topic>Hypocalcemia - surgery</topic><topic>Hypocalcemia - veterinary</topic><topic>Invasiveness</topic><topic>Minimally Invasive Surgical Procedures - methods</topic><topic>Minimally Invasive Surgical Procedures - veterinary</topic><topic>Morbidity</topic><topic>Muscles</topic><topic>Parathyroid</topic><topic>Parathyroid gland</topic><topic>Parathyroid Neoplasms - diagnostic imaging</topic><topic>Parathyroid Neoplasms - surgery</topic><topic>Parathyroid Neoplasms - veterinary</topic><topic>Parathyroidectomy</topic><topic>Parathyroidectomy - veterinary</topic><topic>Retrospective Studies</topic><topic>Skin diseases</topic><topic>Supplements</topic><topic>Thyroid</topic><topic>Thyroid gland</topic><topic>Thyroidectomy</topic><topic>Ultrasonic imaging</topic><topic>Ultrasonic testing</topic><topic>Ultrasonography, Interventional - veterinary</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Young, Kenneth M.</creatorcontrib><creatorcontrib>Degner, Daniel A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Young, Kenneth M.</au><au>Degner, Daniel A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surgical description and outcome of ultrasound‐guided minimally invasive parathyroidectomy in 50 dogs with primary hyperparathyroidism</atitle><jtitle>Veterinary surgery</jtitle><addtitle>Vet Surg</addtitle><date>2023-01</date><risdate>2023</risdate><volume>52</volume><issue>1</issue><spage>18</spage><epage>25</epage><pages>18-25</pages><issn>0161-3499</issn><eissn>1532-950X</eissn><abstract>Objective
To describe the surgical technique and clinical outcome of minimally invasive parathyroidectomy for primary hyperparathyroidism (PHPT) in the dog.
Animals
Fifty client‐owned dogs with PHPT that underwent minimally invasive parathyroidectomy.
Study design
Retrospective cohort study.
Methods
An ultrasound‐guided mini lateral approach was made via a plane established between the sternocephalicus muscle and sternohyoideus muscles to expose the thyroid gland and enlarged parathyroid gland. Abnormal parathyroid glands were removed en bloc via partial thyroidectomy. The technique for bilateral disease was similar, the skin incision was made on midline and moved laterally to develop the above‐mentioned plane of dissection. Age, sex, breed, bodyweight, ultrasound findings, histopathological diagnosis, surgical time, preoperative clinical signs, and clinical outcome were extracted from the records for descriptive statistics.
Results
A total of 62 glands were surgically removed, including 17 hyperplastic glands (17/62, 27.4%), 34 adenomas (34/62, 54.8%), and two carcinomas (2/62, 3.2%). Hypercalcemia resolved shortly after surgery in 44 dogs (44/45, 97.8%). One dog had recurrent hypercalcemia (1/45, 2.2%), one dog had persistent hypercalcemia (1/45, 2.2%), two dogs had permanent hypocalcemia requiring life‐long calcitriol supplementation (2/45, 4.4%), and one dog died from clinical hypocalcemia (1/45, 2.2%).
Conclusion
Minimally invasive parathyroidectomy was associated with a low morbidity and led to favorable outcomes in 44/45 dogs in this series.
Clinical significance
The results of this study supports the use of minimally invasive parathyroidectomy to treat PHPT in dogs.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>36221891</pmid><doi>10.1111/vsu.13897</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-7855-3751</orcidid><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Wiley Journals |
subjects | 25-Hydroxyvitamin D Animals Calcitriol Carcinoma Dog Diseases - diagnostic imaging Dog Diseases - surgery Dogs Hypercalcemia Hypercalcemia - complications Hypercalcemia - surgery Hypercalcemia - veterinary Hyperparathyroidism Hyperparathyroidism, Primary - surgery Hyperparathyroidism, Primary - veterinary Hypocalcemia Hypocalcemia - complications Hypocalcemia - surgery Hypocalcemia - veterinary Invasiveness Minimally Invasive Surgical Procedures - methods Minimally Invasive Surgical Procedures - veterinary Morbidity Muscles Parathyroid Parathyroid gland Parathyroid Neoplasms - diagnostic imaging Parathyroid Neoplasms - surgery Parathyroid Neoplasms - veterinary Parathyroidectomy Parathyroidectomy - veterinary Retrospective Studies Skin diseases Supplements Thyroid Thyroid gland Thyroidectomy Ultrasonic imaging Ultrasonic testing Ultrasonography, Interventional - veterinary Ultrasound |
title | Surgical description and outcome of ultrasound‐guided minimally invasive parathyroidectomy in 50 dogs with primary hyperparathyroidism |
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