RET rearrangements in non-small cell lung cancer: Evolving treatment landscape and future challenges

The Rearranged during Transfection (RET) oncogene has been extensively investigated in solid malignancies, particularly thyroid cancer and non-small cell lung cancer (NSCLC), and represents an attractive therapeutic target. RET rearrangements occur in 1–2% of lung adenocarcinomas, where they functio...

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Veröffentlicht in:	Biochimica et biophysica acta. Reviews on cancer 2022-11, Vol.1877 (6), p.188810-188810, Article 188810
Hauptverfasser:	Servetto, Alberto, Esposito, Daniela, Ferrara, Roberto, Signorelli, Diego, Belli, Stefania, Napolitano, Fabiana, Santaniello, Antonio, Ciciola, Paola, Formisano, Luigi, Bianco, Roberto
Format:	Artikel
Sprache:	eng
Schlagworte:	NSCLC Oncogene-addicted NSCLC Oncogenic fusions Pralsetinib RET Selpercatinib Tyrosine kinase inhibitors
Online-Zugang:	Volltext
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