Effect of ICRS Lesion Grade on Graft Survival After Medial Meniscal Allograft Transplantation: MRI-Based Objective Evaluation
Background: Data are lacking regarding the survival rate after medial meniscal allograft transplantation (MAT) alone. Furthermore, little information is available about prognostic factors for graft survival that affect the outcomes of medial MAT. Purpose: To investigate the prognostic factors and su...
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| Veröffentlicht in: | The American journal of sports medicine 2022-11, Vol.50 (13), p.3579-3585 |
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| creator | Lee, Seon-Jong Bin, Seong-Il Kim, Jong-Min Lee, Bum-Sik Kim, Seung-Min Lee, Hyo Yeol |
| description | Background:
Data are lacking regarding the survival rate after medial meniscal allograft transplantation (MAT) alone. Furthermore, little information is available about prognostic factors for graft survival that affect the outcomes of medial MAT.
Purpose:
To investigate the prognostic factors and survival rate of allograft after medial MAT.
Study Design:
Case-control study; Level of evidence, 3.
Methods:
The records of 78 consecutive patients who underwent primary medial MAT between 1996 and 2018 were reviewed. Kaplan-Meier survival analysis was performed to analyze the anatomic and clinical survival rates. Anatomic failure was defined as a tear covering >50% of the allograft or unstable peripheral rim. Clinical failure was considered Lysholm score 50% of the allograft. Patient factors affecting anatomic and clinical failure were analyzed.
Results:
The mean follow-up period was 6.9 ± 5.3 years (range, 2-21 years). Anatomic failure was noted in 19 patients (24.4%), and none of these patients had a persistent poor Lysholm score of |
| doi_str_mv | 10.1177/03635465221124897 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2721639259</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_03635465221124897</sage_id><sourcerecordid>2731009020</sourcerecordid><originalsourceid>FETCH-LOGICAL-c345t-c8b4a4efd0e487c25a10c9569ea342f95d95fc1d59ee56850577973d1e4502a73</originalsourceid><addsrcrecordid>eNp1kU9Lw0AQxRdRsFY_gLcFL15S9282601LrYWWQlvPYZvMlpQ0qbtJwYPf3U0rCIqn2dn5vTcPBqFbSgaUKvVAeMyliCVjlDKRaHWGelRKFnEey3PU6-ZRB1yiK--3hBCq4qSHPkfWQtbg2uLJcLHEU_BFXeGxMzng08M2eNm6Q3EwJX6yDTg8g7wIzQyqwmfdb1nWmyO4cqby-9JUjWmCzyOeLSbRs_GQ4_l6GxYVB8Cj4NQe59fowprSw8137aO3l9Fq-BpN5-PJ8GkaZVzIJsqStTACbE5AJCpj0lCSaRlrMFwwq2Wupc1oLjWAjBNJpFJa8ZyCkIQZxfvo_uS7d_V7C75JdyE5lCEo1K1PmWI05ppJHdC7X-i2bl0V0gWKU0I0YSRQ9ERlrvbegU33rtgZ95FSknYHSf8cJGgGJ403G_hx_V_wBe2IiX0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2731009020</pqid></control><display><type>article</type><title>Effect of ICRS Lesion Grade on Graft Survival After Medial Meniscal Allograft Transplantation: MRI-Based Objective Evaluation</title><source>SAGE Complete</source><source>Alma/SFX Local Collection</source><creator>Lee, Seon-Jong ; Bin, Seong-Il ; Kim, Jong-Min ; Lee, Bum-Sik ; Kim, Seung-Min ; Lee, Hyo Yeol</creator><creatorcontrib>Lee, Seon-Jong ; Bin, Seong-Il ; Kim, Jong-Min ; Lee, Bum-Sik ; Kim, Seung-Min ; Lee, Hyo Yeol</creatorcontrib><description>Background:
Data are lacking regarding the survival rate after medial meniscal allograft transplantation (MAT) alone. Furthermore, little information is available about prognostic factors for graft survival that affect the outcomes of medial MAT.
Purpose:
To investigate the prognostic factors and survival rate of allograft after medial MAT.
Study Design:
Case-control study; Level of evidence, 3.
Methods:
The records of 78 consecutive patients who underwent primary medial MAT between 1996 and 2018 were reviewed. Kaplan-Meier survival analysis was performed to analyze the anatomic and clinical survival rates. Anatomic failure was defined as a tear covering >50% of the allograft or unstable peripheral rim. Clinical failure was considered Lysholm score <65 or need for additional surgery such as meniscal repair, revision MAT, realignment osteotomy, and meniscectomy for >50% of the allograft. Patient factors affecting anatomic and clinical failure were analyzed.
Results:
The mean follow-up period was 6.9 ± 5.3 years (range, 2-21 years). Anatomic failure was noted in 19 patients (24.4%), and none of these patients had a persistent poor Lysholm score of <65; of these, 2 patients who underwent meniscal repair also had clinical failure. Clinical failure was noted in 7 patients (9.0%); 4 patients had Lysholm score <65, 2 patients underwent meniscal repair, and 1 patient underwent realignment osteotomy. The estimated 10-year anatomic and clinical survival rates were 73.89% and 87.90%, respectively. Anatomic survival was significantly associated with only high-grade International Cartilage Regeneration & Joint Preservation (ICRS) lesion (ICRS grade 3 or 4) (hazard ratio, 3.171; 95% CI, 1.124-8.944; P = .029). However, the clinical survival rate was not significantly associated with any factors. Patients with low-grade ICRS lesion (ICRS grade 0, 1, or 2) showed a higher estimated 10-year anatomic survival rate compared with patients with high-grade ICRS lesions (87.6% vs 63.3%, respectively; P = .022).
Conclusion:
Low-grade ICRS lesion was associated with higher anatomic survival rate after medial MAT. In patients with high-grade ICRS lesions, the clinical outcome might be good; however, the status of an allograft might be poor. The surgeon should be aware of this and explain to the patient that close observation is necessary.</description><identifier>ISSN: 0363-5465</identifier><identifier>EISSN: 1552-3365</identifier><identifier>DOI: 10.1177/03635465221124897</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Magnetic resonance imaging ; Medical prognosis ; Patients ; Sports medicine ; Survival analysis</subject><ispartof>The American journal of sports medicine, 2022-11, Vol.50 (13), p.3579-3585</ispartof><rights>2022 The Author(s)</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c345t-c8b4a4efd0e487c25a10c9569ea342f95d95fc1d59ee56850577973d1e4502a73</citedby><cites>FETCH-LOGICAL-c345t-c8b4a4efd0e487c25a10c9569ea342f95d95fc1d59ee56850577973d1e4502a73</cites><orcidid>0000-0002-7269-0915 ; 0000-0003-1787-1139</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/03635465221124897$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/03635465221124897$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21798,27901,27902,43597,43598</link.rule.ids></links><search><creatorcontrib>Lee, Seon-Jong</creatorcontrib><creatorcontrib>Bin, Seong-Il</creatorcontrib><creatorcontrib>Kim, Jong-Min</creatorcontrib><creatorcontrib>Lee, Bum-Sik</creatorcontrib><creatorcontrib>Kim, Seung-Min</creatorcontrib><creatorcontrib>Lee, Hyo Yeol</creatorcontrib><title>Effect of ICRS Lesion Grade on Graft Survival After Medial Meniscal Allograft Transplantation: MRI-Based Objective Evaluation</title><title>The American journal of sports medicine</title><addtitle>Am J Sports Med</addtitle><description>Background:
Data are lacking regarding the survival rate after medial meniscal allograft transplantation (MAT) alone. Furthermore, little information is available about prognostic factors for graft survival that affect the outcomes of medial MAT.
Purpose:
To investigate the prognostic factors and survival rate of allograft after medial MAT.
Study Design:
Case-control study; Level of evidence, 3.
Methods:
The records of 78 consecutive patients who underwent primary medial MAT between 1996 and 2018 were reviewed. Kaplan-Meier survival analysis was performed to analyze the anatomic and clinical survival rates. Anatomic failure was defined as a tear covering >50% of the allograft or unstable peripheral rim. Clinical failure was considered Lysholm score <65 or need for additional surgery such as meniscal repair, revision MAT, realignment osteotomy, and meniscectomy for >50% of the allograft. Patient factors affecting anatomic and clinical failure were analyzed.
Results:
The mean follow-up period was 6.9 ± 5.3 years (range, 2-21 years). Anatomic failure was noted in 19 patients (24.4%), and none of these patients had a persistent poor Lysholm score of <65; of these, 2 patients who underwent meniscal repair also had clinical failure. Clinical failure was noted in 7 patients (9.0%); 4 patients had Lysholm score <65, 2 patients underwent meniscal repair, and 1 patient underwent realignment osteotomy. The estimated 10-year anatomic and clinical survival rates were 73.89% and 87.90%, respectively. Anatomic survival was significantly associated with only high-grade International Cartilage Regeneration & Joint Preservation (ICRS) lesion (ICRS grade 3 or 4) (hazard ratio, 3.171; 95% CI, 1.124-8.944; P = .029). However, the clinical survival rate was not significantly associated with any factors. Patients with low-grade ICRS lesion (ICRS grade 0, 1, or 2) showed a higher estimated 10-year anatomic survival rate compared with patients with high-grade ICRS lesions (87.6% vs 63.3%, respectively; P = .022).
Conclusion:
Low-grade ICRS lesion was associated with higher anatomic survival rate after medial MAT. In patients with high-grade ICRS lesions, the clinical outcome might be good; however, the status of an allograft might be poor. The surgeon should be aware of this and explain to the patient that close observation is necessary.</description><subject>Magnetic resonance imaging</subject><subject>Medical prognosis</subject><subject>Patients</subject><subject>Sports medicine</subject><subject>Survival analysis</subject><issn>0363-5465</issn><issn>1552-3365</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp1kU9Lw0AQxRdRsFY_gLcFL15S9282601LrYWWQlvPYZvMlpQ0qbtJwYPf3U0rCIqn2dn5vTcPBqFbSgaUKvVAeMyliCVjlDKRaHWGelRKFnEey3PU6-ZRB1yiK--3hBCq4qSHPkfWQtbg2uLJcLHEU_BFXeGxMzng08M2eNm6Q3EwJX6yDTg8g7wIzQyqwmfdb1nWmyO4cqby-9JUjWmCzyOeLSbRs_GQ4_l6GxYVB8Cj4NQe59fowprSw8137aO3l9Fq-BpN5-PJ8GkaZVzIJsqStTACbE5AJCpj0lCSaRlrMFwwq2Wupc1oLjWAjBNJpFJa8ZyCkIQZxfvo_uS7d_V7C75JdyE5lCEo1K1PmWI05ppJHdC7X-i2bl0V0gWKU0I0YSRQ9ERlrvbegU33rtgZ95FSknYHSf8cJGgGJ403G_hx_V_wBe2IiX0</recordid><startdate>202211</startdate><enddate>202211</enddate><creator>Lee, Seon-Jong</creator><creator>Bin, Seong-Il</creator><creator>Kim, Jong-Min</creator><creator>Lee, Bum-Sik</creator><creator>Kim, Seung-Min</creator><creator>Lee, Hyo Yeol</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>U9A</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7269-0915</orcidid><orcidid>https://orcid.org/0000-0003-1787-1139</orcidid></search><sort><creationdate>202211</creationdate><title>Effect of ICRS Lesion Grade on Graft Survival After Medial Meniscal Allograft Transplantation: MRI-Based Objective Evaluation</title><author>Lee, Seon-Jong ; Bin, Seong-Il ; Kim, Jong-Min ; Lee, Bum-Sik ; Kim, Seung-Min ; Lee, Hyo Yeol</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c345t-c8b4a4efd0e487c25a10c9569ea342f95d95fc1d59ee56850577973d1e4502a73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Magnetic resonance imaging</topic><topic>Medical prognosis</topic><topic>Patients</topic><topic>Sports medicine</topic><topic>Survival analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Seon-Jong</creatorcontrib><creatorcontrib>Bin, Seong-Il</creatorcontrib><creatorcontrib>Kim, Jong-Min</creatorcontrib><creatorcontrib>Lee, Bum-Sik</creatorcontrib><creatorcontrib>Kim, Seung-Min</creatorcontrib><creatorcontrib>Lee, Hyo Yeol</creatorcontrib><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of sports medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Seon-Jong</au><au>Bin, Seong-Il</au><au>Kim, Jong-Min</au><au>Lee, Bum-Sik</au><au>Kim, Seung-Min</au><au>Lee, Hyo Yeol</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of ICRS Lesion Grade on Graft Survival After Medial Meniscal Allograft Transplantation: MRI-Based Objective Evaluation</atitle><jtitle>The American journal of sports medicine</jtitle><addtitle>Am J Sports Med</addtitle><date>2022-11</date><risdate>2022</risdate><volume>50</volume><issue>13</issue><spage>3579</spage><epage>3585</epage><pages>3579-3585</pages><issn>0363-5465</issn><eissn>1552-3365</eissn><abstract>Background:
Data are lacking regarding the survival rate after medial meniscal allograft transplantation (MAT) alone. Furthermore, little information is available about prognostic factors for graft survival that affect the outcomes of medial MAT.
Purpose:
To investigate the prognostic factors and survival rate of allograft after medial MAT.
Study Design:
Case-control study; Level of evidence, 3.
Methods:
The records of 78 consecutive patients who underwent primary medial MAT between 1996 and 2018 were reviewed. Kaplan-Meier survival analysis was performed to analyze the anatomic and clinical survival rates. Anatomic failure was defined as a tear covering >50% of the allograft or unstable peripheral rim. Clinical failure was considered Lysholm score <65 or need for additional surgery such as meniscal repair, revision MAT, realignment osteotomy, and meniscectomy for >50% of the allograft. Patient factors affecting anatomic and clinical failure were analyzed.
Results:
The mean follow-up period was 6.9 ± 5.3 years (range, 2-21 years). Anatomic failure was noted in 19 patients (24.4%), and none of these patients had a persistent poor Lysholm score of <65; of these, 2 patients who underwent meniscal repair also had clinical failure. Clinical failure was noted in 7 patients (9.0%); 4 patients had Lysholm score <65, 2 patients underwent meniscal repair, and 1 patient underwent realignment osteotomy. The estimated 10-year anatomic and clinical survival rates were 73.89% and 87.90%, respectively. Anatomic survival was significantly associated with only high-grade International Cartilage Regeneration & Joint Preservation (ICRS) lesion (ICRS grade 3 or 4) (hazard ratio, 3.171; 95% CI, 1.124-8.944; P = .029). However, the clinical survival rate was not significantly associated with any factors. Patients with low-grade ICRS lesion (ICRS grade 0, 1, or 2) showed a higher estimated 10-year anatomic survival rate compared with patients with high-grade ICRS lesions (87.6% vs 63.3%, respectively; P = .022).
Conclusion:
Low-grade ICRS lesion was associated with higher anatomic survival rate after medial MAT. In patients with high-grade ICRS lesions, the clinical outcome might be good; however, the status of an allograft might be poor. The surgeon should be aware of this and explain to the patient that close observation is necessary.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><doi>10.1177/03635465221124897</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-7269-0915</orcidid><orcidid>https://orcid.org/0000-0003-1787-1139</orcidid></addata></record> |
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| language | eng |
| recordid | cdi_proquest_miscellaneous_2721639259 |
| source | SAGE Complete; Alma/SFX Local Collection |
| subjects | Magnetic resonance imaging Medical prognosis Patients Sports medicine Survival analysis |
| title | Effect of ICRS Lesion Grade on Graft Survival After Medial Meniscal Allograft Transplantation: MRI-Based Objective Evaluation |
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