R11 modified tumor cell membrane nanovesicle-camouflaged nanoparticles with enhanced targeting and mucus-penetrating efficiency for intravesical chemotherapy for bladder cancer

Intravesical chemotherapy is generally used in the clinic for treating bladder cancer (BCa), but its efficacy is limited due to the permeation barrier and side effects caused by the off-targeting of normal urothelial cells. In this study, BCa cell-derived membrane nanovesicles were used as drug carr...

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Veröffentlicht in:	Journal of controlled release 2022-11, Vol.351, p.834-846
Hauptverfasser:	Zheng, Bin, Liu, Zhenghong, Wang, Heng, Sun, Li, Lai, Wing-Fu, Zhang, Haibao, Wang, Jinxue, Liu, Yang, Qin, Xiaowen, Qi, Xiaolong, Wang, Shuai, Shen, Youqing, Zhang, Pu, Zhang, Dahong
Format:	Artikel
Sprache:	eng
Schlagworte:	Bladder cancer Cell membrane-camouflaged nanoparticle Intravesical therapy Mucus-penetrating
Online-Zugang:	Volltext
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