KIF4 enforces the progression of colorectal cancer by inhibiting the autophagy via activating the Hedgehog signaling pathway

This work firstly scrutinized the effect of KIF4 on the progression of CRC. KIF4 expression in CRC clinical tissues and cells was evaluated by real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and Western blot. Cell counting kit-8 assay, Transwell invasion and migratio...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Archives of biochemistry and biophysics 2022-11, Vol.731, p.109423-109423, Article 109423
Hauptverfasser:	Fu, Yuxiang, Li, Fang, Sun, Xiao, Zhu, Chang, Fan, Baohang, Zhong, Keli
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Cell Line, Tumor Cell Movement - physiology Cell Proliferation - physiology Colorectal Neoplasms - pathology CRC Hedgehog pathway Hedgehog Proteins Humans KIF4 Kinesins - metabolism Neoplasm Invasiveness Progression Propylamines Sirolimus
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!