The prognostic and predictive values of differential expression of exosomal receptor tyrosine kinases and associated with the PI3K/AKT/mTOR signaling in breast cancer patients undergoing neoadjuvant chemotherapy

Purpose Cancer cell-derived exosomes are the mediator of the tumor microenvironment and the molecular content of exosomes presents a promising prognostic or predictive marker in tumor progression and the treatment response of cancer patients. The aim of this study was to identify the expression leve...

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Veröffentlicht in:	Clinical & translational oncology 2023-02, Vol.25 (2), p.460-472
Hauptverfasser:	Guney Eskiler, Gamze, Kazan, Nur, Haciefendi, Ayten, Deveci Ozkan, Asuman, Ozdemir, Kayhan, Ozen, Mirac, Kocer, Havva Belma, Yilmaz, Fahri, Kaleli, Suleyman, Sahin, Elvan, Bilir, Cemil
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - pathology Female Humans Medicine Medicine & Public Health Neoadjuvant Therapy Oncology Phosphatidylinositol 3-Kinases - metabolism Prognosis Proto-Oncogene Proteins c-akt - metabolism Receptor Protein-Tyrosine Kinases Receptor, Platelet-Derived Growth Factor beta - therapeutic use Research Article RNA, Messenger TOR Serine-Threonine Kinases - metabolism Tumor Microenvironment Tyrosine - therapeutic use
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