Photodissociation of nitric oxide from designed ruthenium nitrosyl complex: Studies on wound healing and antibacterial activity

A photoactivable NO releasing complex [Ru(L1-2)(PPh3)(NO)Cl2](PF6)(1a) have been synthesized by complex [RuL1-2(PPh3)2Cl2](1). Newly designed bidentate ligands, i.e., 4-methoxy-N′-phenyl-N'-(pyridin-2-ylmethyl)benzohydrazide(L1) and 4-nitro-N′-phenyl-N'-(pyridin-2-ylmethyl)benzohydrazide (...

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Veröffentlicht in:	Nitric oxide 2022-12, Vol.129, p.30-40
Hauptverfasser:	Singh, Sain, Navale, Govinda R., Mahale, Mithil, Chaudhary, Virendra Kumar, Kodam, Kisan, Ghosh, Kaushik
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-bacterial acitivity Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Coordination Complexes - chemistry Coordination Complexes - pharmacology Escherichia coli Griess assay Ligands Mice Myoglobin trapping Nitric Oxide Photolabile nitric oxide Ruthenium - chemistry Ruthenium - pharmacology Ruthenium nitrosyl complexes Wound Healing
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