Schizosaccharomyces pombe MAP kinase Sty1 promotes survival of Δppr10 cells with defective mitochondrial protein synthesis

Deletion of the Schizosaccharomyces pombe pentatricopeptide repeat gene ppr10 severely impairs mitochondrial translation, resulting in defective oxidative phosphorylation (OXPHOS). ppr10 deletion also induces iron starvation response, resulting in increased reactive oxygen species (ROS) production a...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2022-11, Vol.152, p.106308, Article 106308
Hauptverfasser:	Hu, Yue, Luo, Ying, Yin, Dan, Zhao, Lan, Wang, Yirong, Yao, Rui, Zhang, Pan, Wu, Xiaoyu, Li, Minjie, Hidalgo, Elena, Huang, Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene Expression Regulation, Fungal Heat-Shock Proteins - genetics Mitochondria Mitochondrial Proteins - metabolism Mitogen-Activated Protein Kinases - metabolism Oxidative Stress Pap1 PPR protein Schizosaccharomyces Schizosaccharomyces pombe Schizosaccharomyces pombe Proteins - genetics Schizosaccharomyces pombe Proteins - metabolism Sty1
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