Assessment of an artificial intelligence aid for the detection of appendicular skeletal fractures in children and young adults by senior and junior radiologists

Background As the number of conventional radiographic examinations in pediatric emergency departments increases, so, too, does the number of reading errors by radiologists. Objective The aim of this study is to investigate the ability of artificial intelligence (AI) to improve the detection of fract...

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Veröffentlicht in:Pediatric radiology 2022-10, Vol.52 (11), p.2215-2226
Hauptverfasser: Nguyen, Toan, Maarek, Richard, Hermann, Anne-Laure, Kammoun, Amina, Marchi, Antoine, Khelifi-Touhami, Mohamed R., Collin, Mégane, Jaillard, Aliénor, Kompel, Andrew J., Hayashi, Daichi, Guermazi, Ali, Le Pointe, Hubert Ducou
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container_end_page 2226
container_issue 11
container_start_page 2215
container_title Pediatric radiology
container_volume 52
creator Nguyen, Toan
Maarek, Richard
Hermann, Anne-Laure
Kammoun, Amina
Marchi, Antoine
Khelifi-Touhami, Mohamed R.
Collin, Mégane
Jaillard, Aliénor
Kompel, Andrew J.
Hayashi, Daichi
Guermazi, Ali
Le Pointe, Hubert Ducou
description Background As the number of conventional radiographic examinations in pediatric emergency departments increases, so, too, does the number of reading errors by radiologists. Objective The aim of this study is to investigate the ability of artificial intelligence (AI) to improve the detection of fractures by radiologists in children and young adults. Materials and methods A cohort of 300 anonymized radiographs performed for the detection of appendicular fractures in patients ages 2 to 21 years was collected retrospectively. The ground truth for each examination was established after an independent review by two radiologists with expertise in musculoskeletal imaging. Discrepancies were resolved by consensus with a third radiologist. Half of the 300 examinations showed at least 1 fracture. Radiographs were read by three senior pediatric radiologists and five radiology residents in the usual manner and then read again immediately after with the help of AI. Results The mean sensitivity for all groups was 73.3% (110/150) without AI; it increased significantly by almost 10% ( P
doi_str_mv 10.1007/s00247-022-05496-3
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Objective The aim of this study is to investigate the ability of artificial intelligence (AI) to improve the detection of fractures by radiologists in children and young adults. Materials and methods A cohort of 300 anonymized radiographs performed for the detection of appendicular fractures in patients ages 2 to 21 years was collected retrospectively. The ground truth for each examination was established after an independent review by two radiologists with expertise in musculoskeletal imaging. Discrepancies were resolved by consensus with a third radiologist. Half of the 300 examinations showed at least 1 fracture. Radiographs were read by three senior pediatric radiologists and five radiology residents in the usual manner and then read again immediately after with the help of AI. Results The mean sensitivity for all groups was 73.3% (110/150) without AI; it increased significantly by almost 10% ( P &lt;0.001) to 82.8% (125/150) with AI. For junior radiologists, it increased by 10.3% ( P &lt;0.001) and for senior radiologists by 8.2% ( P =0.08). On average, there was no significant change in specificity (from 89.6% to 90.3% [+0.7%, P =0.28]); for junior radiologists, specificity increased from 86.2% to 87.6% (+1.4%, P =0.42) and for senior radiologists, it decreased from 95.1% to 94.9% (-0.2%, P =0.23). The stand-alone sensitivity and specificity of the AI were, respectively, 91% and 90%. Conclusion With the help of AI, sensitivity increased by an average of 10% without significantly decreasing specificity in fracture detection in a predominantly pediatric population.</description><identifier>ISSN: 0301-0449</identifier><identifier>EISSN: 1432-1998</identifier><identifier>DOI: 10.1007/s00247-022-05496-3</identifier><identifier>PMID: 36169667</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescent ; Adult ; Adults ; Artificial Intelligence ; Child ; Child, Preschool ; Children ; Emergency medical care ; Emergency medical services ; Fractures ; Fractures, Bone - diagnostic imaging ; Humans ; Imaging ; Medical diagnosis ; Medicine ; Medicine &amp; Public Health ; Neuroradiology ; Nuclear Medicine ; Oncology ; Original Article ; Pediatrics ; Radiographs ; Radiography ; Radiologists ; Radiology ; Retrospective Studies ; Sensitivity ; Ultrasound ; Young Adult ; Young adults</subject><ispartof>Pediatric radiology, 2022-10, Vol.52 (11), p.2215-2226</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022. Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-353ec1813a1d01625898442618a3e21ddc4e8231774fe94100c5594a9d86be283</citedby><cites>FETCH-LOGICAL-c375t-353ec1813a1d01625898442618a3e21ddc4e8231774fe94100c5594a9d86be283</cites><orcidid>0000-0002-9235-445X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00247-022-05496-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00247-022-05496-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36169667$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nguyen, Toan</creatorcontrib><creatorcontrib>Maarek, Richard</creatorcontrib><creatorcontrib>Hermann, Anne-Laure</creatorcontrib><creatorcontrib>Kammoun, Amina</creatorcontrib><creatorcontrib>Marchi, Antoine</creatorcontrib><creatorcontrib>Khelifi-Touhami, Mohamed R.</creatorcontrib><creatorcontrib>Collin, Mégane</creatorcontrib><creatorcontrib>Jaillard, Aliénor</creatorcontrib><creatorcontrib>Kompel, Andrew J.</creatorcontrib><creatorcontrib>Hayashi, Daichi</creatorcontrib><creatorcontrib>Guermazi, Ali</creatorcontrib><creatorcontrib>Le Pointe, Hubert Ducou</creatorcontrib><title>Assessment of an artificial intelligence aid for the detection of appendicular skeletal fractures in children and young adults by senior and junior radiologists</title><title>Pediatric radiology</title><addtitle>Pediatr Radiol</addtitle><addtitle>Pediatr Radiol</addtitle><description>Background As the number of conventional radiographic examinations in pediatric emergency departments increases, so, too, does the number of reading errors by radiologists. Objective The aim of this study is to investigate the ability of artificial intelligence (AI) to improve the detection of fractures by radiologists in children and young adults. Materials and methods A cohort of 300 anonymized radiographs performed for the detection of appendicular fractures in patients ages 2 to 21 years was collected retrospectively. The ground truth for each examination was established after an independent review by two radiologists with expertise in musculoskeletal imaging. Discrepancies were resolved by consensus with a third radiologist. Half of the 300 examinations showed at least 1 fracture. Radiographs were read by three senior pediatric radiologists and five radiology residents in the usual manner and then read again immediately after with the help of AI. Results The mean sensitivity for all groups was 73.3% (110/150) without AI; it increased significantly by almost 10% ( P &lt;0.001) to 82.8% (125/150) with AI. For junior radiologists, it increased by 10.3% ( P &lt;0.001) and for senior radiologists by 8.2% ( P =0.08). On average, there was no significant change in specificity (from 89.6% to 90.3% [+0.7%, P =0.28]); for junior radiologists, specificity increased from 86.2% to 87.6% (+1.4%, P =0.42) and for senior radiologists, it decreased from 95.1% to 94.9% (-0.2%, P =0.23). The stand-alone sensitivity and specificity of the AI were, respectively, 91% and 90%. Conclusion With the help of AI, sensitivity increased by an average of 10% without significantly decreasing specificity in fracture detection in a predominantly pediatric population.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adults</subject><subject>Artificial Intelligence</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Emergency medical care</subject><subject>Emergency medical services</subject><subject>Fractures</subject><subject>Fractures, Bone - diagnostic imaging</subject><subject>Humans</subject><subject>Imaging</subject><subject>Medical diagnosis</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Neuroradiology</subject><subject>Nuclear Medicine</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Pediatrics</subject><subject>Radiographs</subject><subject>Radiography</subject><subject>Radiologists</subject><subject>Radiology</subject><subject>Retrospective Studies</subject><subject>Sensitivity</subject><subject>Ultrasound</subject><subject>Young Adult</subject><subject>Young adults</subject><issn>0301-0449</issn><issn>1432-1998</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kctuEzEUhi1ERUPLC7BAltiwGerbeMbLquImVWJD1yPHPpM6TOzgYy_yNjwqTlJAYsHKlvz9n-3zE_Kas_ecseEGGRNq6JgQHeuV0Z18RlZcSdFxY8bnZMUk4x1TylySl4hbxpjsuXxBLqXm2mg9rMjPW0RA3EEsNM3URmpzCXNwwS40xALLEjYQHVAbPJ1TpuURqIcCroQUT5n9HqIPri42U_wOC5SWnbN1pWbAZqHuMSw-Q5NHTw-pxg21vi4F6fpAEWJo3uPRtp622fqQlrQJWPCaXMx2QXj1tF6Rh48fvt197u6_fvpyd3vfOTn0pZO9BMdHLi33jGvRj2ZUSmg-WgmCe-8UjELyYVAzGNXm5_reKGv8qNcgRnlF3p29-5x-VMAy7QK69n0bIVWcxMBHo3lvdEPf_oNuU82xva5Ros2--WWjxJlyOSFmmKd9DjubDxNn07G_6dzf1PqbTv1Nx9CbJ3Vd78D_ifwurAHyDGA7ihvIf-_-j_YXUBinnw</recordid><startdate>20221001</startdate><enddate>20221001</enddate><creator>Nguyen, Toan</creator><creator>Maarek, Richard</creator><creator>Hermann, Anne-Laure</creator><creator>Kammoun, Amina</creator><creator>Marchi, Antoine</creator><creator>Khelifi-Touhami, Mohamed R.</creator><creator>Collin, Mégane</creator><creator>Jaillard, Aliénor</creator><creator>Kompel, Andrew J.</creator><creator>Hayashi, Daichi</creator><creator>Guermazi, Ali</creator><creator>Le Pointe, Hubert Ducou</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9235-445X</orcidid></search><sort><creationdate>20221001</creationdate><title>Assessment of an artificial intelligence aid for the detection of appendicular skeletal fractures in children and young adults by senior and junior radiologists</title><author>Nguyen, Toan ; 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Objective The aim of this study is to investigate the ability of artificial intelligence (AI) to improve the detection of fractures by radiologists in children and young adults. Materials and methods A cohort of 300 anonymized radiographs performed for the detection of appendicular fractures in patients ages 2 to 21 years was collected retrospectively. The ground truth for each examination was established after an independent review by two radiologists with expertise in musculoskeletal imaging. Discrepancies were resolved by consensus with a third radiologist. Half of the 300 examinations showed at least 1 fracture. Radiographs were read by three senior pediatric radiologists and five radiology residents in the usual manner and then read again immediately after with the help of AI. Results The mean sensitivity for all groups was 73.3% (110/150) without AI; it increased significantly by almost 10% ( P &lt;0.001) to 82.8% (125/150) with AI. For junior radiologists, it increased by 10.3% ( P &lt;0.001) and for senior radiologists by 8.2% ( P =0.08). On average, there was no significant change in specificity (from 89.6% to 90.3% [+0.7%, P =0.28]); for junior radiologists, specificity increased from 86.2% to 87.6% (+1.4%, P =0.42) and for senior radiologists, it decreased from 95.1% to 94.9% (-0.2%, P =0.23). The stand-alone sensitivity and specificity of the AI were, respectively, 91% and 90%. Conclusion With the help of AI, sensitivity increased by an average of 10% without significantly decreasing specificity in fracture detection in a predominantly pediatric population.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>36169667</pmid><doi>10.1007/s00247-022-05496-3</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-9235-445X</orcidid></addata></record>
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subjects Adolescent
Adult
Adults
Artificial Intelligence
Child
Child, Preschool
Children
Emergency medical care
Emergency medical services
Fractures
Fractures, Bone - diagnostic imaging
Humans
Imaging
Medical diagnosis
Medicine
Medicine & Public Health
Neuroradiology
Nuclear Medicine
Oncology
Original Article
Pediatrics
Radiographs
Radiography
Radiologists
Radiology
Retrospective Studies
Sensitivity
Ultrasound
Young Adult
Young adults
title Assessment of an artificial intelligence aid for the detection of appendicular skeletal fractures in children and young adults by senior and junior radiologists
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