Glycan-selective in-situ growth of thermoresponsive polymers for thermoprecipitation and enrichment of N-glycoprotein/glycopeptides

In view of the biological significance and micro-heterogeneity of protein glycosylation for human health, specific enrichment of N-glycosylated proteins/peptides from complex biological samples is a prerequisite for the discovery of disease biomarkers and clinical diagnosis. In this work, we propose...

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Veröffentlicht in:Talanta (Oxford) 2023-02, Vol.253, p.123956-123956, Article 123956
Hauptverfasser: Shu, Jingjing, Xiong, Wenli, Zhang, Ran, Ma, Shanyun, Zhou, Kaiqiang, Wang, Xuwei, Yan, Fen, Huang, Da, Li, Jianhua, Wu, Yuanzi, He, Jian'an
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