A novel matrix metalloproteinases-cleavable hydrogel loading deferoxamine accelerates diabetic wound healing

The hyperglycemia microenvironment of diabetic foot ulcer (DFU) led to impaired angiogenesis and delayed wound healing. An elevated matrix metalloproteinase (MMP) is one of the significant factors to delay healing. Herein, we designed a deferoxamine (DFO)-loaded MMP responsive hydrogel, thus promoti...

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Veröffentlicht in:	International journal of biological macromolecules 2022-12, Vol.222, p.1551-1559
Hauptverfasser:	Li, Ning, Zhan, Aiyan, Jiang, Yiguo, Liu, Hongzhuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Deferoxamine Diabetic wound healing Hydrogel MMP-cleavable Self-healing
Online-Zugang:	Volltext
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