Stabilization of leukocytes from cerebrospinal fluid for central immunophenotypic evaluation in multicenter clinical trials

Analysis of cerebrospinal fluid (CSF) represents a valuable window into the pathogenesis of neuroinflammatory diseases, such as multiple sclerosis (MS). However, analysis of the cellular fraction of CSF is often neglected because CSF cells die rapidly ex vivo. Immunophenotyping of CSF cells in multi...

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Veröffentlicht in:Journal of immunological methods 2022-11, Vol.510, p.113344-113344, Article 113344
Hauptverfasser: Mexhitaj, Ina, Lim, Noha, Fernandez-Velasco, Jose I., Zrzavy, Tobias, Harris, Kristina M., Muraro, Paolo A., Villar, Luisa M., Bar-Or, Amit, Cooney, Laura A.
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