Chlorine exposure and intensive exercise induces airway hyperreactivity in a 3-week murine exercise model

Exercise-induced bronchoconstriction (EIB) is defined as acute narrowing of the airways during or immediately after exercise. EIB has a high prevalence in elite swimmers probably due to the high ventilation rate and exposure to the chlorine by-products. It is still puzzling which pathophysiological...

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Veröffentlicht in:	The Science of the total environment 2022-10, Vol.843, p.157046-157046, Article 157046
Hauptverfasser:	Decaesteker, Tatjana, Jonckheere, Anne-Charlotte, Vanhoffelen, Eliane, Schauvaerts, Jens, Verhalle, Tulasi, Cremer, Jonathan, Dilissen, Ellen, Rodewald, Hans-Reimer, Dupont, Lieven, Bullens, Dominique M.A., Vanoirbeek, Jeroen A.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	adaptive immunity Airway inflammation Animal model animal models blood serum breathing bronchoconstriction chlorine Chlorine exposure cytokines environment Epithelial damage epithelium exercise Exercise-induced bronchoconstriction flow cytometry gene expression inflammation lungs mice permeability tap water tight junctions
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