Achromobacter spp. prevalence and adaptation in cystic fibrosis lung infection
Bacteria belonging to the genus Achromobacter are widely distributed in natural environments and have been recognized as emerging pathogens for their contribution to a wide range of human infections. In particular, patients with cystic fibrosis (CF) are the subjects most frequently colonized by Achr...
Gespeichert in:
| Veröffentlicht in: | Microbiological research 2022-10, Vol.263, p.127140, Article 127140 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | 127140 |
| container_title | Microbiological research |
| container_volume | 263 |
| creator | Veschetti, Laura Boaretti, Marzia Saitta, Giulia Maria Passarelli Mantovani, Rebeca Lleò, Maria M. Sandri, Angela Malerba, Giovanni |
| description | Bacteria belonging to the genus Achromobacter are widely distributed in natural environments and have been recognized as emerging pathogens for their contribution to a wide range of human infections. In particular, patients with cystic fibrosis (CF) are the subjects most frequently colonized by Achromobacter spp., which can cause persistent infections in their respiratory tract. Although many clinical aspects and pathogenic mechanisms still remain to be elucidated, Achromobacter spp. have been a source of expanding interest in recent years. This review examines the current literature regarding Achromobacter spp. role in CF, focusing on taxonomy, prevalence in CF lung infections, genomic characteristics, and adaptation strategies including modifications of metabolism and virulence, acquisition of antibiotic resistance, exchange of mobile genetic elements and development of hypermutation. |
| doi_str_mv | 10.1016/j.micres.2022.127140 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2718283782</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S094450132200180X</els_id><sourcerecordid>2718283782</sourcerecordid><originalsourceid>FETCH-LOGICAL-c385t-e91b2135afbfba4cce7bd64efe20556648affebe85a2838289654106cb7967913</originalsourceid><addsrcrecordid>eNp9kEtLxDAUhYMoOI7-AxdZumlN0jRNN8Iw-IJBN7oOSXqjGfoy6QzMvzelrl1dOJxzuOdD6JaSnBIq7vd5522AmDPCWE5ZRTk5QysqqMyIYMU5WpGa86wktLhEVzHuCaG8lmyF3jb2OwzdYLSdIOA4jjkeAxx1C70FrPsG60aPk5780GPfY3uKk7fYeROG6CNuD_1X0h3Y2XGNLpxuI9z83TX6fHr82L5ku_fn1-1ml9lCllMGNTWMFqV2xhnNrYXKNIKDA0bKUggutXNgQJaayUIyWYuSUyKsqWpR1bRYo7uldwzDzwHipDofLbSt7mE4RJUQpFRRSZasfLHa9HAM4NQYfKfDSVGiZnxqrxZ8asanFnwp9rDEIM04eggqWj8zaXxIW1Uz-P8LfgFRjntD</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2718283782</pqid></control><display><type>article</type><title>Achromobacter spp. prevalence and adaptation in cystic fibrosis lung infection</title><source>Elsevier ScienceDirect Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Veschetti, Laura ; Boaretti, Marzia ; Saitta, Giulia Maria ; Passarelli Mantovani, Rebeca ; Lleò, Maria M. ; Sandri, Angela ; Malerba, Giovanni</creator><creatorcontrib>Veschetti, Laura ; Boaretti, Marzia ; Saitta, Giulia Maria ; Passarelli Mantovani, Rebeca ; Lleò, Maria M. ; Sandri, Angela ; Malerba, Giovanni</creatorcontrib><description>Bacteria belonging to the genus Achromobacter are widely distributed in natural environments and have been recognized as emerging pathogens for their contribution to a wide range of human infections. In particular, patients with cystic fibrosis (CF) are the subjects most frequently colonized by Achromobacter spp., which can cause persistent infections in their respiratory tract. Although many clinical aspects and pathogenic mechanisms still remain to be elucidated, Achromobacter spp. have been a source of expanding interest in recent years. This review examines the current literature regarding Achromobacter spp. role in CF, focusing on taxonomy, prevalence in CF lung infections, genomic characteristics, and adaptation strategies including modifications of metabolism and virulence, acquisition of antibiotic resistance, exchange of mobile genetic elements and development of hypermutation.</description><identifier>ISSN: 0944-5013</identifier><identifier>EISSN: 1618-0623</identifier><identifier>DOI: 10.1016/j.micres.2022.127140</identifier><language>eng</language><publisher>Elsevier GmbH</publisher><subject>Achromobacter ; Adaptation ; antibiotic resistance ; Cystic fibrosis ; genomics ; genus ; humans ; Infection ; Lung ; lungs ; metabolism ; virulence</subject><ispartof>Microbiological research, 2022-10, Vol.263, p.127140, Article 127140</ispartof><rights>2022 Elsevier GmbH</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c385t-e91b2135afbfba4cce7bd64efe20556648affebe85a2838289654106cb7967913</citedby><cites>FETCH-LOGICAL-c385t-e91b2135afbfba4cce7bd64efe20556648affebe85a2838289654106cb7967913</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S094450132200180X$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids></links><search><creatorcontrib>Veschetti, Laura</creatorcontrib><creatorcontrib>Boaretti, Marzia</creatorcontrib><creatorcontrib>Saitta, Giulia Maria</creatorcontrib><creatorcontrib>Passarelli Mantovani, Rebeca</creatorcontrib><creatorcontrib>Lleò, Maria M.</creatorcontrib><creatorcontrib>Sandri, Angela</creatorcontrib><creatorcontrib>Malerba, Giovanni</creatorcontrib><title>Achromobacter spp. prevalence and adaptation in cystic fibrosis lung infection</title><title>Microbiological research</title><description>Bacteria belonging to the genus Achromobacter are widely distributed in natural environments and have been recognized as emerging pathogens for their contribution to a wide range of human infections. In particular, patients with cystic fibrosis (CF) are the subjects most frequently colonized by Achromobacter spp., which can cause persistent infections in their respiratory tract. Although many clinical aspects and pathogenic mechanisms still remain to be elucidated, Achromobacter spp. have been a source of expanding interest in recent years. This review examines the current literature regarding Achromobacter spp. role in CF, focusing on taxonomy, prevalence in CF lung infections, genomic characteristics, and adaptation strategies including modifications of metabolism and virulence, acquisition of antibiotic resistance, exchange of mobile genetic elements and development of hypermutation.</description><subject>Achromobacter</subject><subject>Adaptation</subject><subject>antibiotic resistance</subject><subject>Cystic fibrosis</subject><subject>genomics</subject><subject>genus</subject><subject>humans</subject><subject>Infection</subject><subject>Lung</subject><subject>lungs</subject><subject>metabolism</subject><subject>virulence</subject><issn>0944-5013</issn><issn>1618-0623</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp9kEtLxDAUhYMoOI7-AxdZumlN0jRNN8Iw-IJBN7oOSXqjGfoy6QzMvzelrl1dOJxzuOdD6JaSnBIq7vd5522AmDPCWE5ZRTk5QysqqMyIYMU5WpGa86wktLhEVzHuCaG8lmyF3jb2OwzdYLSdIOA4jjkeAxx1C70FrPsG60aPk5780GPfY3uKk7fYeROG6CNuD_1X0h3Y2XGNLpxuI9z83TX6fHr82L5ku_fn1-1ml9lCllMGNTWMFqV2xhnNrYXKNIKDA0bKUggutXNgQJaayUIyWYuSUyKsqWpR1bRYo7uldwzDzwHipDofLbSt7mE4RJUQpFRRSZasfLHa9HAM4NQYfKfDSVGiZnxqrxZ8asanFnwp9rDEIM04eggqWj8zaXxIW1Uz-P8LfgFRjntD</recordid><startdate>202210</startdate><enddate>202210</enddate><creator>Veschetti, Laura</creator><creator>Boaretti, Marzia</creator><creator>Saitta, Giulia Maria</creator><creator>Passarelli Mantovani, Rebeca</creator><creator>Lleò, Maria M.</creator><creator>Sandri, Angela</creator><creator>Malerba, Giovanni</creator><general>Elsevier GmbH</general><scope>6I.</scope><scope>AAFTH</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7S9</scope><scope>L.6</scope></search><sort><creationdate>202210</creationdate><title>Achromobacter spp. prevalence and adaptation in cystic fibrosis lung infection</title><author>Veschetti, Laura ; Boaretti, Marzia ; Saitta, Giulia Maria ; Passarelli Mantovani, Rebeca ; Lleò, Maria M. ; Sandri, Angela ; Malerba, Giovanni</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c385t-e91b2135afbfba4cce7bd64efe20556648affebe85a2838289654106cb7967913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Achromobacter</topic><topic>Adaptation</topic><topic>antibiotic resistance</topic><topic>Cystic fibrosis</topic><topic>genomics</topic><topic>genus</topic><topic>humans</topic><topic>Infection</topic><topic>Lung</topic><topic>lungs</topic><topic>metabolism</topic><topic>virulence</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Veschetti, Laura</creatorcontrib><creatorcontrib>Boaretti, Marzia</creatorcontrib><creatorcontrib>Saitta, Giulia Maria</creatorcontrib><creatorcontrib>Passarelli Mantovani, Rebeca</creatorcontrib><creatorcontrib>Lleò, Maria M.</creatorcontrib><creatorcontrib>Sandri, Angela</creatorcontrib><creatorcontrib>Malerba, Giovanni</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>CrossRef</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>Microbiological research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Veschetti, Laura</au><au>Boaretti, Marzia</au><au>Saitta, Giulia Maria</au><au>Passarelli Mantovani, Rebeca</au><au>Lleò, Maria M.</au><au>Sandri, Angela</au><au>Malerba, Giovanni</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Achromobacter spp. prevalence and adaptation in cystic fibrosis lung infection</atitle><jtitle>Microbiological research</jtitle><date>2022-10</date><risdate>2022</risdate><volume>263</volume><spage>127140</spage><pages>127140-</pages><artnum>127140</artnum><issn>0944-5013</issn><eissn>1618-0623</eissn><abstract>Bacteria belonging to the genus Achromobacter are widely distributed in natural environments and have been recognized as emerging pathogens for their contribution to a wide range of human infections. In particular, patients with cystic fibrosis (CF) are the subjects most frequently colonized by Achromobacter spp., which can cause persistent infections in their respiratory tract. Although many clinical aspects and pathogenic mechanisms still remain to be elucidated, Achromobacter spp. have been a source of expanding interest in recent years. This review examines the current literature regarding Achromobacter spp. role in CF, focusing on taxonomy, prevalence in CF lung infections, genomic characteristics, and adaptation strategies including modifications of metabolism and virulence, acquisition of antibiotic resistance, exchange of mobile genetic elements and development of hypermutation.</abstract><pub>Elsevier GmbH</pub><doi>10.1016/j.micres.2022.127140</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0944-5013 |
| ispartof | Microbiological research, 2022-10, Vol.263, p.127140, Article 127140 |
| issn | 0944-5013 1618-0623 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2718283782 |
| source | Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Achromobacter Adaptation antibiotic resistance Cystic fibrosis genomics genus humans Infection Lung lungs metabolism virulence |
| title | Achromobacter spp. prevalence and adaptation in cystic fibrosis lung infection |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T11%3A45%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Achromobacter%20spp.%20prevalence%20and%20adaptation%20in%20cystic%20fibrosis%20lung%20infection&rft.jtitle=Microbiological%20research&rft.au=Veschetti,%20Laura&rft.date=2022-10&rft.volume=263&rft.spage=127140&rft.pages=127140-&rft.artnum=127140&rft.issn=0944-5013&rft.eissn=1618-0623&rft_id=info:doi/10.1016/j.micres.2022.127140&rft_dat=%3Cproquest_cross%3E2718283782%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2718283782&rft_id=info:pmid/&rft_els_id=S094450132200180X&rfr_iscdi=true |