Pharmacokinetics of tildipirosin in horses after intravenous and intramuscular administration and its potential muscle damage

Tildipirosin is a novel semisynthetic macrolide antibiotic exclusively used in veterinary practice to treat respiratory infections. There are no pharmacokinetic or safety information available regarding the use of tildipirosin after intramuscular administration in horses. Thus, the objective of this...

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Veröffentlicht in:	Research in veterinary science 2022-12, Vol.152, p.20-25
Hauptverfasser:	Galecio, Juan Sebastian, Escudero, Elisa, Badillo, Elena, Marín, Pedro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics Bioavailability Calcium-binding protein Cardiotoxicity Creatine Creatine kinase cross-over studies Damage detection Drug dosages Haptoglobin haptoglobins Horses Infections Inflammation intramuscular injection Intravenous administration intravenous injection Kinases Liquid chromatography Macrolides Muscles Pharmacokinetics Pharmacology Plasma Pneumonia Quality control Safety Tildipirosin Troponin veterinary clinics Veterinary medicine
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