Alternatives to animal models and their application in the discovery of species susceptibility to SARS-CoV-2 and other respiratory infectious pathogens: A review

The emergence of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inspired rapid research efforts targeting the host range, pathogenesis and transmission mechanisms, and the development of antiviral strategies. Genetically modified mi...

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Veröffentlicht in:	Veterinary Pathology 2022-07, Vol.59 (4), p.565-577
Hauptverfasser:	Runft, Sandra, Färber, Iris, Krüger, Johannes, Krüger, Nadine, Armando, Federico, Rocha, Cheila, Pöhlmann, Stefan, Burigk, Laura, Leitzen, Eva, Ciurkiewicz, Malgorzata, Braun, Armin, Schneider, Daniel, Baumgärtner, Lars, Freisleben, Bernd, Baumgärtner, Wolfgang
Format:	Artikel
Sprache:	eng
Schlagworte:	animal pathology Animals Antiviral Agents - therapeutic use cell culture COVID-19 - veterinary COVID-19 infection Cricetinae Disease Models, Animal disease transmission epithelium Ferrets host range liquid-air interface Lung - pathology lungs Macaca mulatta Mice organoids pathogenesis pathophysiology SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 therapeutics zoonoses
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