Mutation of D201G near the receptor binding site significantly drives antigenic drift of circulating H9N2 subtype avian influenza virus

The H9N2 subtype of avian influenza virus (H9N2 AIV) has caused significant losses in chicken flocks throughout China. Our previous research has shown that field isolates of H9N2 underwent antigenic drift to evolve into distinct groups with significant antigenic divergence from the commercially avai...

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Veröffentlicht in:	Transboundary and emerging diseases 2022-11, Vol.69 (6), p.3485-3493
Hauptverfasser:	Xia, Jing, Luo, Yu‐Wen, Dong, Meng‐Yi, Li, Yong‐Xin, Wang, An‐Dong, Li, Nian‐Ling, Shen, Yu‐Xi, Li, Shu‐Yun, Cui, Min, Han, Xin‐Feng, Yu, Song‐Cheng, Li, Min, Huang, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Antigenic determinants Antigenic drift Antigenic Drift and Shift Antigenicity Antigens Avian flu avian influenza virus Binding Sites Chickens China - epidemiology Drift evolution Growth kinetics H9N2 Hemagglutinin Glycoproteins, Influenza Virus - genetics Influenza Influenza A Virus, H9N2 Subtype Influenza in Birds Mutation Phylogeny RBS Receptors Substitutes Viruses
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