Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin

Preservation of a small population of cancer stem cells (CSCs) within a heterogeneous carcinoma serves as a paradigm to understand how select cells in a tissue maintain their undifferentiated status. In both embryogenesis and cancer, Snail has been correlated with stemness, but the molecular underpi...

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Veröffentlicht in:	Cell reports (Cambridge) 2022-09, Vol.40 (12), p.111390-111390, Article 111390
Hauptverfasser:	Badarinath, Krithika, Dam, Binita, Kataria, Sunny, Zirmire, Ravindra K., Dey, Rakesh, Kansagara, Gaurav, Ajnabi, Johan, Hegde, Akshay, Singh, Randhir, Masudi, Tafheem, Sambath, Janani, Sachithanandan, Sasikala P., Kumar, Prashant, Gulyani, Akash, He, You-Wen, Krishna, Sudhir, Jamora, Colin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer stem cells carcinoma EMT Mindin SFK skin cancer Snail STAT3 Tumor heterogeneity
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