Screw loosening in angulation-correcting single implant restorations: A systematic review of in vitro studies

Various options are available to allow angle correction for screw-retained restorations for malaligned implants, including angled abutments, angled screw channel abutments, and angled implants. However, the effect these angle correction components have on prosthetic screw loosening is unclear. The purpose of this systematic review was to assess the effect of angled abutments, angled screw channel abutments, and angled implants on prosthetic screw loosening. This manuscript followed the Preferred Reporting Items for the Systematic Review and Meta-Analyses (PRISMA) statement. Searches were performed through 31 December 2021 in PubMed/MEDLINE, EMBASE, and Web of Science with no year limit targeting in vitro studies evaluating the effect of angulation correction components on screw loosening. A total of 460 articles were identified. After removing duplicates, 306 titles were screened. Nine of the remaining 36 articles selected for full-text analysis met the selection criteria. The qualitative analysis used data from 394 implants. All studies featured straight abutments as the control group, and, in 8 studies, the angle correction component was included on the level of the abutment. Only in 1 study was the angle correction component at the level of the implant. The angle correction of the prosthetic component varied from 0 degrees in all studies up to a maximum correction of 30 degrees. Statistically significant increases in screw loosening with increasing abutment angle correction were reported by multiple authors (P.05). The only study investigating angle correction at the implant level found significantly less screw loosening (P