Lipid nanoparticle-encapsulated VEGFa siRNA facilitates cartilage formation by suppressing angiogenesis

Cartilage is an important tissue that is widely found in joints, ears, nose and other organs. The limited capacity to regenerate makes cartilage reconstruction an urgent clinical demand. Due to the avascular nature of cartilage, we hypothesized that inhibition of vascularization contributes to carti...

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Veröffentlicht in:	International journal of biological macromolecules 2022-11, Vol.221, p.1313-1324
Hauptverfasser:	Chen, Yi, Chen, Wei, Ren, Yiming, Li, Shuling, Liu, Miao, Xing, Jiahua, Han, Yudi, Chen, Youbai, Tao, Ran, Guo, Lingli, Sui, Xiang, Guo, Quanyi, Liu, Shuyun, Han, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Cartilage tissue engineering GelMA hydrogel Lipid nanoparticles Small interfering RNA
Online-Zugang:	Volltext
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