iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study

Refractoriness to platelet transfusion is a major problem in a small group of patients, and large-scale manufacturing of clinical grade functional platelets ex vivo has remained an elusive goal. Sugimoto et al report on the results of the first clinical trial of an autologous transfusion of induced...

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Veröffentlicht in:	Blood 2022-12, Vol.140 (22), p.2398-2402
Hauptverfasser:	Sugimoto, Naoshi, Kanda, Junya, Nakamura, Sou, Kitano, Toshiyuki, Hishizawa, Masakatsu, Kondo, Tadakazu, Shimizu, Shin, Shigemasa, Akiko, Hirai, Hideyo, Arai, Yasuyuki, Minami, Manabu, Tada, Harue, Momose, Dai, Koh, Ki-Ryang, Nogawa, Masayuki, Watanabe, Naohide, Okamoto, Shinichiro, Handa, Makoto, Sawaguchi, Akira, Matsuyama, Nobuki, Tanaka, Mitsunobu, Hayashi, Tomoya, Fuchizaki, Akihiro, Tani, Yoshihiko, Takaori-Kondo, Akifumi, Eto, Koji
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Platelets Humans Induced Pluripotent Stem Cells Platelet Transfusion Plateletpheresis
Online-Zugang:	Volltext
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