Exosomal microRNA-506 inhibits biological activity of lung adenocarcinoma cells and increases sensitivity to cisplatin-based hyperthermia

Exosomal microRNAs (miRNAs) play a vital role in the occurrence and development of lung adenocarcinoma (LUAD). Based on the bioinformatics analyses, the current study sought to explore the effects of exosomal miR-506 on LUAD cell biology and the efficacy of cisplatin (CDDP)-based hyperthermia (HT)....

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Veröffentlicht in:	Cellular signalling 2022-12, Vol.100, p.110469, Article 110469
Hauptverfasser:	Zhang, Kunming, Sun, Xiwen, Sun, Weikai, Wang, Meng, Han, Fushi
Format:	Artikel
Sprache:	eng
Schlagworte:	ATPase family AAA domain-containing protein 2 Cisplatin-based hyperthermia Exosome Lung adenocarcinoma MicroRNA-506 Phosphatidylinositol 3-kinase/protein kinase B signaling pathway
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