Prenatal, but not postnatal exposure to chlorpyrifos affects social behavior of mice and the excitatory-inhibitory balance in a sex-dependent manner

The balance between excitatory and inhibitory neurotransmitters is essential for proper brain development. An imbalance between these two systems has been associated with neurodevelopmental disorders. On the other hand, literature also associates the massive use of pesticides with the increase of th...

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Veröffentlicht in:	Food and chemical toxicology 2022-11, Vol.169, p.113423-113423, Article 113423
Hauptverfasser:	Biosca-Brull, Judit, Guardia-Escote, Laia, Blanco, Jordi, Basaure, Pia, Cabré, Maria, Sánchez-Santed, Fernando, Domingo, José L., Colomina, Maria Teresa
Format:	Artikel
Sprache:	eng
Schlagworte:	Autism brain Chlorpyrifos corn oil diet Excitatory/inhibitory balance GABA gene expression Glutamate maternal exposure neurotransmitters Social behavior valproic acid
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