circS100A11 enhances M2a macrophage activation and lung inflammation in children with asthma

Background Dysregulation of circRNAs is associated with a variety of human diseases; however, its role in childhood asthma is undefined. Methods The differential expression profiles of circRNAs were analyzed by microarray. The effects and mechanisms by which circRNAs influence macrophage activation...

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Veröffentlicht in:	Allergy (Copenhagen) 2023-06, Vol.78 (6), p.1459-1472
Hauptverfasser:	Liang, Qiuyan, Fu, Jinrong, Wang, Xiang, Liu, Lijuan, Xiao, Wenfeng, Gao, Yajing, Yang, Lan, Yu, Hongmiao, Xie, Xueru, Tu, Zikun, Huang, Saihua, Han, Xiao, Qian, Liling, Zhou, Yufeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asthma Asthma - genetics Cell activation Cell Cycle Proteins Child Children Chromatin circRNA Circular RNA DNA microarrays Humans Immunoprecipitation Inflammation Macrophage Activation Macrophages Mice Monocytes Nucleolin Pneumonia RNA - genetics RNA, Circular S100A11 Stat6 protein Translation
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