YAP1-TEAD1 mediates the perineural invasion of prostate cancer cells induced by cancer-associated fibroblasts

Perineural invasion (PNI) driven by the tumor microenvironment (TME) has emerged as a key pattern of metastasis of prostate cancer (PCa), while its underlying mechanism is still elusive. Here, we identified increased CAFs and YAP1 expression levels in patients with metastatic PCa. In the cultured PC...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular basis of disease 2022-12, Vol.1868 (12), p.166540-166540, Article 166540
Hauptverfasser:	Shen, Tianyu, Li, Yang, Wang, Dekun, Su, Yu, Li, Gang, Shang, Zhiqun, Niu, Yuanjie, Tan, Xiaoyue
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer-associated fibroblast Perineural invasion Prostate cancer Yes-associated protein (YAP1)
Online-Zugang:	Volltext
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