Growth Patterns of Children With Short Stature in Adulthood According to Auxological Status and Maturity at Birth

Prematurity carries a risk for impaired postnatal growth and long-term growth restriction. Especially children born SGA seem vulnerable for poor growth, as a persistent short stature can be observed in app 10-15% of these children. In this study we aimed to recognize differences in growth patterns o...

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Veröffentlicht in:The journal of clinical endocrinology and metabolism 2022-11, Vol.107 (12), p.3320-3327
Hauptverfasser: Pfäffle, Roland, Knüpfer, Matthias, Göbert, Melanie, Vogel, Mandy, Gausche, Ruth, Beger, Christoph, Keller, Eberhard, Körner, Antje, Thome, Ulrich, Kiess, Wieland
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Sprache:eng
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Zusammenfassung:Prematurity carries a risk for impaired postnatal growth and long-term growth restriction. Especially children born SGA seem vulnerable for poor growth, as a persistent short stature can be observed in app 10-15% of these children. In this study we aimed to recognize differences in growth patterns of children according to sex, maturity, and auxological status at birth facilitating earlier identification of small-for-gestational-age (SGA) children with adult short stature. The growth data of 44 791 infants born between January 1, 1980, and December 30, 2012, among 2 pediatric cohorts with follow-up through December 31, 2020, were analyzed. A total of 5698 children with birth data had measurements at near final height (nfh) and at least 2 further points. Preterm children (gestational age
ISSN:0021-972X
1945-7197
DOI:10.1210/clinem/dgac510