Transcriptome analysis reveals the essential role of NK2 homeobox 1/thyroid transcription factor 1 (NKX2-1/TTF-1) in gastric adenocarcinoma of fundic-gland type

Background Gastric adenocarcinoma of fundic-gland type (GA-FG) is a gastric malignancy with little relation to Helicobacter pylori . Clinical characteristics of GA-FG have been established, but molecular mechanisms leading to tumorigenesis have not yet been elucidated. Methods We subjected three GA-...

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Veröffentlicht in:	Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2023-01, Vol.26 (1), p.44-54
Hauptverfasser:	Fukagawa, Kazushi, Takahashi, Yu, Yamamichi, Nobutake, Kageyama-Yahara, Natsuko, Sakaguchi, Yoshiki, Obata, Miho, Cho, Rina, Sakuma, Nobuyuki, Nagao, Sayaka, Miura, Yuko, Tamura, Naoki, Ohki, Daisuke, Mizutani, Hiroya, Yakabi, Seiichi, Minatsuki, Chihiro, Niimi, Keiko, Tsuji, Yosuke, Yamamichi, Mitsue, Shigi, Narumi, Tomida, Shuta, Abe, Hiroyuki, Ushiku, Tetsuo, Koike, Kazuhiko, Fujishiro, Mitsuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Adenocarcinoma Adenocarcinoma - genetics Adenocarcinoma - pathology Cancer Cancer Research DNA microarrays Ectopic expression Gastric cancer Gastroenterology Gene expression Gene Expression Profiling Genes, Homeobox Homeobox Humans Immunohistochemistry Malignancy Medicine Medicine & Public Health Molecular modelling Mucosa Oncology Original Article Protein B Stomach Neoplasms - genetics Stomach Neoplasms - pathology Surgical Oncology Thyroid gland Thyroid Nuclear Factor 1 - genetics Thyroid transcription factor 1 Transcription factors Transcriptomes Tumorigenesis
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