Programmable Assembly of Multivalent DNA‐Protein Superstructures for Tumor Imaging and Targeted Therapy

Programmable DNA materials hold great potential in biochemical and biomedical researches, yet the complicated synthesis, and the low stability and targeting efficacy in complex biological milieu limit their clinical translations. Here we show a one‐pot assembly of DNA‐protein superstructures as drug...

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Veröffentlicht in:	Angewandte Chemie International Edition 2022-11, Vol.61 (44), p.e202211505-n/a
Hauptverfasser:	Xu, Zhen, Shi, Tianhui, Mo, Fengye, Yu, Wenqian, Shen, Yu, Jiang, Qunying, Wang, Fuan, Liu, Xiaoqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Animal models Aptamers Assembly Biomedical materials Biomimetics Cancer Therapy Cell culture Clinical trials Deoxyribonucleic acid DNA DNA Nanostructures Drug Delivery Effectiveness Lung cancer Medical research Multivalency Nanomaterials Nanospheres Nanotechnology Oligonucleotides Polymers Protamine sulfate Proteins Selectivity Self-Assembly Side effects Stability Superstructures Translations Tumors
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