Drug-induced acne with elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis

•Some patients report new or worsening acne after starting elexacaftor/tezacaftor/ivacaftor.•The immunologic basis of this adverse effect is unclear.•Treatment may require trial and error with combination topical therapies or systemic therapies. Elexacaftor/tezacaftor/ivacaftor (ELX-TEZ-IVA) is a Cy...

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Veröffentlicht in:	Journal of cystic fibrosis 2022-11, Vol.21 (6), p.1066-1069
Hauptverfasser:	Hudson, Brionna N., Jacobs, Hollyann R., Philbrick, Alexander, Zhou, Xiaolong A., Simonsen, Michelle M., Safirstein, Julie A., Rotolo, Shannon M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acne vulgaris Acne Vulgaris - chemically induced Acne Vulgaris - drug therapy Aminophenols - adverse effects Benzodioxoles - adverse effects Chloride Channel Agonists - adverse effects Cystic fibrosis Cystic Fibrosis - drug therapy Cystic Fibrosis - genetics Cystic Fibrosis Transmembrane Conductance Regulator - genetics Drug-Related side effects and adverse reactions Elexacaftor Humans Mutation
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