Fusobacterium nucleatum aggravates ulcerative colitis through promoting gut microbiota dysbiosis and dysmetabolism

Background The correlation between periodontitis and ulcerative colitis (UC) has drawn widespread attention recently. Fusobacterium nucleatum (F. nucleatum) as a periodontal pathogen also has reservoirs in gut and may play a role in intestinal diseases. However, its role in the pathogenesis of UC is...

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Veröffentlicht in:	Journal of periodontology (1970) 2023-03, Vol.94 (3), p.405-418
Hauptverfasser:	Lin, Shulan, Zhang, Xiaoyue, Zhu, Xuanzhi, Jiao, Junwei, Wu, Yafei, Li, Yan, Zhao, Lei
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveolar Bone Loss Animals Colitis, Ulcerative - microbiology Colitis, Ulcerative - pathology Disease Models, Animal Dysbiosis Fusobacterium nucleatum Gastrointestinal Microbiome Inflammation metabolite Mice Mice, Inbred C57BL periodontal‐systemic disease interactions periodontitis RNA, Ribosomal, 16S
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