Open-Source Automated Insulin Delivery in Type 1 Diabetes
In this randomized trial, an open-source automated insulin delivery system controlled glucose time-in-range values significantly better than sensor-augmented insulin-pump therapy.
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| Veröffentlicht in: | The New England journal of medicine 2022-09, Vol.387 (10), p.869-881 |
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| container_title | The New England journal of medicine |
| container_volume | 387 |
| creator | Burnside, Mercedes J. Lewis, Dana M. Crocket, Hamish R. Meier, Renee A. Williman, Jonathan A. Sanders, Olivia J. Jefferies, Craig A. Faherty, Ann M. Paul, Ryan G. Lever, Claire S. Price, Sarah K.J. Frewen, Carla M. Jones, Shirley D. Gunn, Tim C. Lampey, Christina Wheeler, Benjamin J. de Bock, Martin I. |
| description | In this randomized trial, an open-source automated insulin delivery system controlled glucose time-in-range values significantly better than sensor-augmented insulin-pump therapy. |
| doi_str_mv | 10.1056/NEJMoa2203913 |
| format | Article |
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All rights reserved.</rights><rights>Copyright © 2022 Massachusetts Medical Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c390t-4cf241fdd7ebb2f4e681a185e9394d11330d6564ec6f98fce23a7a4fdf8dea2a3</citedby><cites>FETCH-LOGICAL-c390t-4cf241fdd7ebb2f4e681a185e9394d11330d6564ec6f98fce23a7a4fdf8dea2a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa2203913$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2711550862?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,781,785,2760,2761,26107,27928,27929,52386,54068,64389,64391,64393,72473</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36069869$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burnside, Mercedes J.</creatorcontrib><creatorcontrib>Lewis, Dana M.</creatorcontrib><creatorcontrib>Crocket, Hamish R.</creatorcontrib><creatorcontrib>Meier, Renee A.</creatorcontrib><creatorcontrib>Williman, Jonathan A.</creatorcontrib><creatorcontrib>Sanders, Olivia J.</creatorcontrib><creatorcontrib>Jefferies, Craig A.</creatorcontrib><creatorcontrib>Faherty, Ann M.</creatorcontrib><creatorcontrib>Paul, Ryan G.</creatorcontrib><creatorcontrib>Lever, Claire S.</creatorcontrib><creatorcontrib>Price, Sarah K.J.</creatorcontrib><creatorcontrib>Frewen, Carla M.</creatorcontrib><creatorcontrib>Jones, Shirley D.</creatorcontrib><creatorcontrib>Gunn, Tim C.</creatorcontrib><creatorcontrib>Lampey, Christina</creatorcontrib><creatorcontrib>Wheeler, Benjamin J.</creatorcontrib><creatorcontrib>de Bock, Martin I.</creatorcontrib><title>Open-Source Automated Insulin Delivery in Type 1 Diabetes</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>In this randomized trial, an open-source automated insulin delivery system controlled glucose time-in-range values significantly better than sensor-augmented insulin-pump therapy.</description><subject>Adolescent</subject><subject>Adolescent Medicine</subject><subject>Adult</subject><subject>Age</subject><subject>Aged</subject><subject>Algorithms</subject><subject>Allergy</subject><subject>Australia</subject><subject>Autoimmune Disease</subject><subject>Autoimmune diseases</subject><subject>Automation</subject><subject>Blood Glucose - analysis</subject><subject>Child</subject><subject>Childhood Diseases</subject><subject>Children</subject><subject>Clinical Medicine</subject><subject>Clinical trials</subject><subject>Diabetes</subject><subject>Diabetes mellitus (insulin dependent)</subject><subject>Diabetes Mellitus, Type 1 - blood</subject><subject>Diabetes Mellitus, Type 1 - drug therapy</subject><subject>Diabetic ketoacidosis</subject><subject>Endocrinology</subject><subject>Glucose monitoring</subject><subject>Hemoglobin</subject><subject>Humans</subject><subject>Hypoglycemia</subject><subject>Hypoglycemic Agents - administration & dosage</subject><subject>Immunology</subject><subject>Infusion Pumps</subject><subject>Insulin</subject><subject>Insulin - administration & dosage</subject><subject>Ketoacidosis</subject><subject>Middle Aged</subject><subject>Outpatient-Based Clinical Medicine</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Pediatrics General</subject><subject>Regulatory approval</subject><subject>Sensors</subject><subject>Smartphones</subject><subject>Teenagers</subject><subject>Young Adult</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp10M1LwzAYBvAgipvTo1cpiOClmq-myXFsUyfTHZznkjZvoKNfNq3Q_97opqDge8l7-PGQ90HonOAbgiNx-7x4fKo1pZgpwg7QmESMhZxjcYjGGFMZ8lixETpxbov9EK6O0YgJLJQUaozUuoEqfKn7NoNg2nd1qTswwbJyfZFXwRyK_B3aIfD7ZmggIME81yl04E7RkdWFg7P9O0Gvd4vN7CFcre-Xs-kqzJjCXcgzSzmxxsSQptRyEJJoIiNQTHFDCGPYiEhwyIRV0mZAmY41t8ZKA5pqNkHXu9ymrd96cF1S5i6DotAV1L1LaOxDsPKHeXr5h279YZX_3ZeKIiwF9SrcqaytnWvBJk2bl7odEoKTz06TX516f7FP7dMSzI_-LtGDqx0oS5dUsC3_CfoAJE97aQ</recordid><startdate>20220908</startdate><enddate>20220908</enddate><creator>Burnside, Mercedes J.</creator><creator>Lewis, Dana M.</creator><creator>Crocket, Hamish R.</creator><creator>Meier, Renee A.</creator><creator>Williman, Jonathan A.</creator><creator>Sanders, Olivia J.</creator><creator>Jefferies, Craig A.</creator><creator>Faherty, Ann M.</creator><creator>Paul, Ryan G.</creator><creator>Lever, Claire S.</creator><creator>Price, Sarah K.J.</creator><creator>Frewen, Carla M.</creator><creator>Jones, Shirley D.</creator><creator>Gunn, Tim C.</creator><creator>Lampey, Christina</creator><creator>Wheeler, Benjamin J.</creator><creator>de Bock, Martin I.</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20220908</creationdate><title>Open-Source Automated Insulin Delivery in Type 1 Diabetes</title><author>Burnside, Mercedes J. ; Lewis, Dana M. ; Crocket, Hamish R. ; Meier, Renee A. ; Williman, Jonathan A. ; Sanders, Olivia J. ; Jefferies, Craig A. ; Faherty, Ann M. ; Paul, Ryan G. ; Lever, Claire S. ; Price, Sarah K.J. ; Frewen, Carla M. ; Jones, Shirley D. ; Gunn, Tim C. ; Lampey, Christina ; Wheeler, Benjamin J. ; de Bock, Martin I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c390t-4cf241fdd7ebb2f4e681a185e9394d11330d6564ec6f98fce23a7a4fdf8dea2a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adolescent</topic><topic>Adolescent Medicine</topic><topic>Adult</topic><topic>Age</topic><topic>Aged</topic><topic>Algorithms</topic><topic>Allergy</topic><topic>Australia</topic><topic>Autoimmune Disease</topic><topic>Autoimmune diseases</topic><topic>Automation</topic><topic>Blood Glucose - 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| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2022-09, Vol.387 (10), p.869-881 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Adolescent Adolescent Medicine Adult Age Aged Algorithms Allergy Australia Autoimmune Disease Autoimmune diseases Automation Blood Glucose - analysis Child Childhood Diseases Children Clinical Medicine Clinical trials Diabetes Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Diabetic ketoacidosis Endocrinology Glucose monitoring Hemoglobin Humans Hypoglycemia Hypoglycemic Agents - administration & dosage Immunology Infusion Pumps Insulin Insulin - administration & dosage Ketoacidosis Middle Aged Outpatient-Based Clinical Medicine Patients Pediatrics Pediatrics General Regulatory approval Sensors Smartphones Teenagers Young Adult |
| title | Open-Source Automated Insulin Delivery in Type 1 Diabetes |
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