Substrates and Inhibitors of the Organic Cation Transporter 3 and Comparison with OCT1 and OCT2

Organic cation transporters (OCTs) 1, 2, and 3 facilitate cellular uptake of structurally diverse endogenous and exogenous substances. However, their substrate and inhibitor specificity are not fully understood. We performed a broad in vitro screening for OCT3 substrates and inhibitors, allowing us...

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Veröffentlicht in:	Journal of medicinal chemistry 2022-09, Vol.65 (18), p.12403-12416
Hauptverfasser:	Gebauer, Lukas, Jensen, Ole, Brockmöller, Jürgen, Dücker, Christof
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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