ATG5: A central autophagy regulator implicated in various human diseases

Autophagy, an intracellular conserved degradative process, plays a central role in the renewal/recycling of a cell to maintain the homeostasis of nutrients and energy within the cell. ATG5, a key component of autophagy, regulates the formation of the autophagosome, a hallmark of autophagy. ATG5 bind...

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Veröffentlicht in:	Cell biochemistry and function 2022-10, Vol.40 (7), p.650-667
Hauptverfasser:	Changotra, Harish, Kaur, Sargeet, Yadav, Suresh Singh, Gupta, Girdhari Lal, Parkash, Jyoti, Duseja, Ajay
Format:	Artikel
Sprache:	eng
Schlagworte:	ATG12–ATG5/ATG16L1 ATG5 ATG5 polymorphism autophagosome Autophagy Biological activity Genetic diversity Genetic variance Homeostasis Nutrients Physiology Reviews Roles Therapeutic targets
Online-Zugang:	Volltext
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