(Pro)renin receptor inhibition attenuated liver steatosis, inflammation, and fibrosis in mice with steatohepatitis

The (Pro)renin receptor (PRR) is reportedly involved in hepatic lipid metabolism and hepatocyte PRR knockdown protects mice against hepatosteatosis. However, the impact of PRR inhibition on liver inflammation and fibrosis in nonalcoholic steatohepatitis (NASH) remains unclear. Herein, C57BL/6 mice w...

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Veröffentlicht in:	The FASEB journal 2022-10, Vol.36 (10), p.e22526-n/a
Hauptverfasser:	Hsieh, Yun‐Cheng, Wu, Pei‐Shan, Lin, Yi‐Tsung, Huang, Yi‐Hsiang, Hou, Ming‐Chih, Lee, Kuei‐Chuan, Lin, Han‐Chieh
Format:	Artikel
Sprache:	eng
Schlagworte:	chronic liver injury gene silencing handle region peptide lipid metabolism nonalcoholic fatty liver disease
Online-Zugang:	Volltext
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