Predictive factors for anastomotic leakage after colon cancer surgery
in colon cancer surgery, anastomotic fistula (AF) is considered the most feared complication. The purpose of this study was to identify predictive factors associated with anastomotic fistula after colon cancer surgical resection and to describe the impact of this complication on mortality and postop...
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| Veröffentlicht in: | The Pan African medical journal 2022, Vol.42, p.129 |
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| creator | Zouari, Amine Masmoudi, Abderrahmen Khanfir, Fatma Ketata, Salma Rejab, Haithem Bouzid, Ahmed Loukil, Issam Zribi, Imen Talbi, Skander Abdelhedi, Amine Abid, Bassem Boujelben, Salah |
| description | in colon cancer surgery, anastomotic fistula (AF) is considered the most feared complication. The purpose of this study was to identify predictive factors associated with anastomotic fistula after colon cancer surgical resection and to describe the impact of this complication on mortality and postoperative length of stay.
we conducted a retrospective, descriptive and analytical study in the Department of General Surgery at the Habib Bourguiba Hospital in Sfax, Tunisia from 1
January 2013 to 31 December 2020.
we collected data from the medical records of 163 patients who had undergone surgery for colon cancer. The average age of patients was 62.7 years with a sex ratio of 1.36. The postoperative course was uneventful in 64.4% of cases and complicated in 35.6% of cases. Surgical morbidity was mainly due to anastomotic fistulas (22 patients). This study demonstrated that predictors of the development of this complication were: diabetes p = 0.04, smoking p = 0.01, hypoalbuminaemia p = 0.01, preoperative haemoglobin less than 10g/dl, p < 0.01, anastomotic fistula located in the left colonic angle p = 0.02, perioperative transfusion p |
| doi_str_mv | 10.11604/pamj.2022.42.129.33570 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_2709914130</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2709914130</sourcerecordid><originalsourceid>FETCH-LOGICAL-p141t-ba0f86a538bf48c2dedd6a0eb1b11f2312389582386c6e9933c6f07ba1081e403</originalsourceid><addsrcrecordid>eNpNT11LwzAUDaK4Of0L2kdfWm-SLk0fZcwPGOiDPpfb9GZ0tk1NUmH_3okTfDkfcDiHw9gNh4xzBfndiP0uEyBElouMizKTclnACZvzUhapVlqf_tMzdhHCDkApLeGczaQCBTqHOVu_empaE9svSiya6HxIrPMJDhii611sTdIRfuCWErSRfGJc54bE4GAOJkx-S35_yc4sdoGujrxg7w_rt9VTunl5fF7db9KR5zymNYLVCpdS1zbXRjTUNAqBal5zboXkQupyqQ-ojKKylNIoC0WNHDSnHOSC3f72jt59ThRi1bfBUNfhQG4KlSigLA9T8id6fYxOdU9NNfq2R7-v_q7Lb3DPXPc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2709914130</pqid></control><display><type>article</type><title>Predictive factors for anastomotic leakage after colon cancer surgery</title><source>African Journals Online (Open Access)</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>PubMed Central Open Access</source><creator>Zouari, Amine ; Masmoudi, Abderrahmen ; Khanfir, Fatma ; Ketata, Salma ; Rejab, Haithem ; Bouzid, Ahmed ; Loukil, Issam ; Zribi, Imen ; Talbi, Skander ; Abdelhedi, Amine ; Abid, Bassem ; Boujelben, Salah</creator><creatorcontrib>Zouari, Amine ; Masmoudi, Abderrahmen ; Khanfir, Fatma ; Ketata, Salma ; Rejab, Haithem ; Bouzid, Ahmed ; Loukil, Issam ; Zribi, Imen ; Talbi, Skander ; Abdelhedi, Amine ; Abid, Bassem ; Boujelben, Salah</creatorcontrib><description>in colon cancer surgery, anastomotic fistula (AF) is considered the most feared complication. The purpose of this study was to identify predictive factors associated with anastomotic fistula after colon cancer surgical resection and to describe the impact of this complication on mortality and postoperative length of stay.
we conducted a retrospective, descriptive and analytical study in the Department of General Surgery at the Habib Bourguiba Hospital in Sfax, Tunisia from 1
January 2013 to 31 December 2020.
we collected data from the medical records of 163 patients who had undergone surgery for colon cancer. The average age of patients was 62.7 years with a sex ratio of 1.36. The postoperative course was uneventful in 64.4% of cases and complicated in 35.6% of cases. Surgical morbidity was mainly due to anastomotic fistulas (22 patients). This study demonstrated that predictors of the development of this complication were: diabetes p = 0.04, smoking p = 0.01, hypoalbuminaemia p = 0.01, preoperative haemoglobin less than 10g/dl, p < 0.01, anastomotic fistula located in the left colonic angle p = 0.02, perioperative transfusion p <0.01, and duration of surgery longer than 180 min p = 0.04. Moreover, the occurrence of anastomotic fistula was associated with specific mortality rate (9%) and significantly prolonged postoperative length of stay.
the prevention of anastomotic fistulas should be part of a multimodal approach based on the correction of nutritional deficiencies and possible pre-operative anemia.</description><identifier>ISSN: 1937-8688</identifier><identifier>EISSN: 1937-8688</identifier><identifier>DOI: 10.11604/pamj.2022.42.129.33570</identifier><identifier>PMID: 36060840</identifier><language>fre</language><publisher>Uganda</publisher><subject>Anastomotic Leak - epidemiology ; Anastomotic Leak - etiology ; Anastomotic Leak - prevention & control ; Colonic Neoplasms - complications ; Colonic Neoplasms - surgery ; Digestive System Surgical Procedures ; Humans ; Middle Aged ; Retrospective Studies</subject><ispartof>The Pan African medical journal, 2022, Vol.42, p.129</ispartof><rights>Copyright: Amine Zouari et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36060840$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zouari, Amine</creatorcontrib><creatorcontrib>Masmoudi, Abderrahmen</creatorcontrib><creatorcontrib>Khanfir, Fatma</creatorcontrib><creatorcontrib>Ketata, Salma</creatorcontrib><creatorcontrib>Rejab, Haithem</creatorcontrib><creatorcontrib>Bouzid, Ahmed</creatorcontrib><creatorcontrib>Loukil, Issam</creatorcontrib><creatorcontrib>Zribi, Imen</creatorcontrib><creatorcontrib>Talbi, Skander</creatorcontrib><creatorcontrib>Abdelhedi, Amine</creatorcontrib><creatorcontrib>Abid, Bassem</creatorcontrib><creatorcontrib>Boujelben, Salah</creatorcontrib><title>Predictive factors for anastomotic leakage after colon cancer surgery</title><title>The Pan African medical journal</title><addtitle>Pan Afr Med J</addtitle><description>in colon cancer surgery, anastomotic fistula (AF) is considered the most feared complication. The purpose of this study was to identify predictive factors associated with anastomotic fistula after colon cancer surgical resection and to describe the impact of this complication on mortality and postoperative length of stay.
we conducted a retrospective, descriptive and analytical study in the Department of General Surgery at the Habib Bourguiba Hospital in Sfax, Tunisia from 1
January 2013 to 31 December 2020.
we collected data from the medical records of 163 patients who had undergone surgery for colon cancer. The average age of patients was 62.7 years with a sex ratio of 1.36. The postoperative course was uneventful in 64.4% of cases and complicated in 35.6% of cases. Surgical morbidity was mainly due to anastomotic fistulas (22 patients). This study demonstrated that predictors of the development of this complication were: diabetes p = 0.04, smoking p = 0.01, hypoalbuminaemia p = 0.01, preoperative haemoglobin less than 10g/dl, p < 0.01, anastomotic fistula located in the left colonic angle p = 0.02, perioperative transfusion p <0.01, and duration of surgery longer than 180 min p = 0.04. Moreover, the occurrence of anastomotic fistula was associated with specific mortality rate (9%) and significantly prolonged postoperative length of stay.
the prevention of anastomotic fistulas should be part of a multimodal approach based on the correction of nutritional deficiencies and possible pre-operative anemia.</description><subject>Anastomotic Leak - epidemiology</subject><subject>Anastomotic Leak - etiology</subject><subject>Anastomotic Leak - prevention & control</subject><subject>Colonic Neoplasms - complications</subject><subject>Colonic Neoplasms - surgery</subject><subject>Digestive System Surgical Procedures</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><issn>1937-8688</issn><issn>1937-8688</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNT11LwzAUDaK4Of0L2kdfWm-SLk0fZcwPGOiDPpfb9GZ0tk1NUmH_3okTfDkfcDiHw9gNh4xzBfndiP0uEyBElouMizKTclnACZvzUhapVlqf_tMzdhHCDkApLeGczaQCBTqHOVu_empaE9svSiya6HxIrPMJDhii611sTdIRfuCWErSRfGJc54bE4GAOJkx-S35_yc4sdoGujrxg7w_rt9VTunl5fF7db9KR5zymNYLVCpdS1zbXRjTUNAqBal5zboXkQupyqQ-ojKKylNIoC0WNHDSnHOSC3f72jt59ThRi1bfBUNfhQG4KlSigLA9T8id6fYxOdU9NNfq2R7-v_q7Lb3DPXPc</recordid><startdate>2022</startdate><enddate>2022</enddate><creator>Zouari, Amine</creator><creator>Masmoudi, Abderrahmen</creator><creator>Khanfir, Fatma</creator><creator>Ketata, Salma</creator><creator>Rejab, Haithem</creator><creator>Bouzid, Ahmed</creator><creator>Loukil, Issam</creator><creator>Zribi, Imen</creator><creator>Talbi, Skander</creator><creator>Abdelhedi, Amine</creator><creator>Abid, Bassem</creator><creator>Boujelben, Salah</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2022</creationdate><title>Predictive factors for anastomotic leakage after colon cancer surgery</title><author>Zouari, Amine ; Masmoudi, Abderrahmen ; Khanfir, Fatma ; Ketata, Salma ; Rejab, Haithem ; Bouzid, Ahmed ; Loukil, Issam ; Zribi, Imen ; Talbi, Skander ; Abdelhedi, Amine ; Abid, Bassem ; Boujelben, Salah</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p141t-ba0f86a538bf48c2dedd6a0eb1b11f2312389582386c6e9933c6f07ba1081e403</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2022</creationdate><topic>Anastomotic Leak - epidemiology</topic><topic>Anastomotic Leak - etiology</topic><topic>Anastomotic Leak - prevention & control</topic><topic>Colonic Neoplasms - complications</topic><topic>Colonic Neoplasms - surgery</topic><topic>Digestive System Surgical Procedures</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zouari, Amine</creatorcontrib><creatorcontrib>Masmoudi, Abderrahmen</creatorcontrib><creatorcontrib>Khanfir, Fatma</creatorcontrib><creatorcontrib>Ketata, Salma</creatorcontrib><creatorcontrib>Rejab, Haithem</creatorcontrib><creatorcontrib>Bouzid, Ahmed</creatorcontrib><creatorcontrib>Loukil, Issam</creatorcontrib><creatorcontrib>Zribi, Imen</creatorcontrib><creatorcontrib>Talbi, Skander</creatorcontrib><creatorcontrib>Abdelhedi, Amine</creatorcontrib><creatorcontrib>Abid, Bassem</creatorcontrib><creatorcontrib>Boujelben, Salah</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Pan African medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zouari, Amine</au><au>Masmoudi, Abderrahmen</au><au>Khanfir, Fatma</au><au>Ketata, Salma</au><au>Rejab, Haithem</au><au>Bouzid, Ahmed</au><au>Loukil, Issam</au><au>Zribi, Imen</au><au>Talbi, Skander</au><au>Abdelhedi, Amine</au><au>Abid, Bassem</au><au>Boujelben, Salah</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictive factors for anastomotic leakage after colon cancer surgery</atitle><jtitle>The Pan African medical journal</jtitle><addtitle>Pan Afr Med J</addtitle><date>2022</date><risdate>2022</risdate><volume>42</volume><spage>129</spage><pages>129-</pages><issn>1937-8688</issn><eissn>1937-8688</eissn><abstract>in colon cancer surgery, anastomotic fistula (AF) is considered the most feared complication. The purpose of this study was to identify predictive factors associated with anastomotic fistula after colon cancer surgical resection and to describe the impact of this complication on mortality and postoperative length of stay.
we conducted a retrospective, descriptive and analytical study in the Department of General Surgery at the Habib Bourguiba Hospital in Sfax, Tunisia from 1
January 2013 to 31 December 2020.
we collected data from the medical records of 163 patients who had undergone surgery for colon cancer. The average age of patients was 62.7 years with a sex ratio of 1.36. The postoperative course was uneventful in 64.4% of cases and complicated in 35.6% of cases. Surgical morbidity was mainly due to anastomotic fistulas (22 patients). This study demonstrated that predictors of the development of this complication were: diabetes p = 0.04, smoking p = 0.01, hypoalbuminaemia p = 0.01, preoperative haemoglobin less than 10g/dl, p < 0.01, anastomotic fistula located in the left colonic angle p = 0.02, perioperative transfusion p <0.01, and duration of surgery longer than 180 min p = 0.04. Moreover, the occurrence of anastomotic fistula was associated with specific mortality rate (9%) and significantly prolonged postoperative length of stay.
the prevention of anastomotic fistulas should be part of a multimodal approach based on the correction of nutritional deficiencies and possible pre-operative anemia.</abstract><cop>Uganda</cop><pmid>36060840</pmid><doi>10.11604/pamj.2022.42.129.33570</doi><oa>free_for_read</oa></addata></record> |
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| source | African Journals Online (Open Access); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Anastomotic Leak - epidemiology Anastomotic Leak - etiology Anastomotic Leak - prevention & control Colonic Neoplasms - complications Colonic Neoplasms - surgery Digestive System Surgical Procedures Humans Middle Aged Retrospective Studies |
| title | Predictive factors for anastomotic leakage after colon cancer surgery |
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