Duodenopancreatectomy for PDAC Associated with MALS: A Case Report
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of pancreatic malignancy which occurs in over 90% of such cases. Pancreaticoduodenectomy (PD) is used with a curative purpose for localized PDAC. Case presentation: A 68-year-old woman presented to our service through a transfer from anot...
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Veröffentlicht in: | Chirurgia (Bucharest, Romania : 1990) Romania : 1990), 2022-07, Vol.117 (4), p.493-498 |
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container_title | Chirurgia (Bucharest, Romania : 1990) |
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creator | Moiş, Emil Pop, Cristina Paula Graur, Florin Moldovan, Septimiu Puia, Ion Cosmin Zdrehuş, Claudiu Mureşan, Ioan Hajjar, Nadim Al |
description | Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of pancreatic malignancy which occurs in over 90% of such cases. Pancreaticoduodenectomy (PD) is used with a curative purpose for localized PDAC. Case presentation: A 68-year-old woman presented to our service through a transfer from another service, to be investigated and treated for a head of the pancreas tumor in a tertiary referral hospital. After a complete clinical and paraclinical evaluation, the patient was diagnosed with a PDAC and also with a median arcuate ligament syndrome (MALS). The surgical treatment was considered adequate, therefore, the patient underwent a PD with transmesocolic hepaticojejunostomy, pancreaticogastric anastomosis, precolic end-to-side gastrojejunostomy, Witzel jejunostomy and with the help of the cardiovascular surgery team from the Heart Institute, Cluj- Napoca, an aortohepatic bypass using saphenous vein graft was performed. Conclusion: Bypass was essential because the blood flow in the proper hepatic artery was not restored after sectioning the median arcuate ligament and clamping the gastroduodenal artery. The patient had a favorable outcome. The particularity of the present case consists of the complete occlusion of the celiac trunk by MALS and the total vascularization of the supramesocolic organs due to the superior mesenteric artery through the gastroduodenal artery. |
doi_str_mv | 10.21614/chirurgia.2757 |
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Pancreaticoduodenectomy (PD) is used with a curative purpose for localized PDAC. Case presentation: A 68-year-old woman presented to our service through a transfer from another service, to be investigated and treated for a head of the pancreas tumor in a tertiary referral hospital. After a complete clinical and paraclinical evaluation, the patient was diagnosed with a PDAC and also with a median arcuate ligament syndrome (MALS). The surgical treatment was considered adequate, therefore, the patient underwent a PD with transmesocolic hepaticojejunostomy, pancreaticogastric anastomosis, precolic end-to-side gastrojejunostomy, Witzel jejunostomy and with the help of the cardiovascular surgery team from the Heart Institute, Cluj- Napoca, an aortohepatic bypass using saphenous vein graft was performed. Conclusion: Bypass was essential because the blood flow in the proper hepatic artery was not restored after sectioning the median arcuate ligament and clamping the gastroduodenal artery. The patient had a favorable outcome. The particularity of the present case consists of the complete occlusion of the celiac trunk by MALS and the total vascularization of the supramesocolic organs due to the superior mesenteric artery through the gastroduodenal artery.</description><identifier>ISSN: 1221-9118</identifier><identifier>DOI: 10.21614/chirurgia.2757</identifier><identifier>PMID: 36049108</identifier><language>eng</language><publisher>Romania</publisher><subject>Aged ; Carcinoma, Pancreatic Ductal - surgery ; Constriction, Pathologic - surgery ; Female ; Humans ; Median Arcuate Ligament Syndrome - complications ; Median Arcuate Ligament Syndrome - diagnosis ; Median Arcuate Ligament Syndrome - surgery ; Pancreatic Neoplasms ; Pancreatic Neoplasms - complications ; Pancreatic Neoplasms - surgery ; Pancreaticoduodenectomy - adverse effects ; Treatment Outcome</subject><ispartof>Chirurgia (Bucharest, Romania : 1990), 2022-07, Vol.117 (4), p.493-498</ispartof><rights>Celsius.</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-775c0163dabce9b62038ff5cf1ccfc31368b783c86e28411c77bf0b4731fb4d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36049108$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moiş, Emil</creatorcontrib><creatorcontrib>Pop, Cristina Paula</creatorcontrib><creatorcontrib>Graur, Florin</creatorcontrib><creatorcontrib>Moldovan, Septimiu</creatorcontrib><creatorcontrib>Puia, Ion Cosmin</creatorcontrib><creatorcontrib>Zdrehuş, Claudiu</creatorcontrib><creatorcontrib>Mureşan, Ioan</creatorcontrib><creatorcontrib>Hajjar, Nadim Al</creatorcontrib><title>Duodenopancreatectomy for PDAC Associated with MALS: A Case Report</title><title>Chirurgia (Bucharest, Romania : 1990)</title><addtitle>Chirurgia (Bucur)</addtitle><description>Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of pancreatic malignancy which occurs in over 90% of such cases. Pancreaticoduodenectomy (PD) is used with a curative purpose for localized PDAC. Case presentation: A 68-year-old woman presented to our service through a transfer from another service, to be investigated and treated for a head of the pancreas tumor in a tertiary referral hospital. After a complete clinical and paraclinical evaluation, the patient was diagnosed with a PDAC and also with a median arcuate ligament syndrome (MALS). The surgical treatment was considered adequate, therefore, the patient underwent a PD with transmesocolic hepaticojejunostomy, pancreaticogastric anastomosis, precolic end-to-side gastrojejunostomy, Witzel jejunostomy and with the help of the cardiovascular surgery team from the Heart Institute, Cluj- Napoca, an aortohepatic bypass using saphenous vein graft was performed. Conclusion: Bypass was essential because the blood flow in the proper hepatic artery was not restored after sectioning the median arcuate ligament and clamping the gastroduodenal artery. The patient had a favorable outcome. The particularity of the present case consists of the complete occlusion of the celiac trunk by MALS and the total vascularization of the supramesocolic organs due to the superior mesenteric artery through the gastroduodenal artery.</description><subject>Aged</subject><subject>Carcinoma, Pancreatic Ductal - surgery</subject><subject>Constriction, Pathologic - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Median Arcuate Ligament Syndrome - complications</subject><subject>Median Arcuate Ligament Syndrome - diagnosis</subject><subject>Median Arcuate Ligament Syndrome - surgery</subject><subject>Pancreatic Neoplasms</subject><subject>Pancreatic Neoplasms - complications</subject><subject>Pancreatic Neoplasms - surgery</subject><subject>Pancreaticoduodenectomy - adverse effects</subject><subject>Treatment Outcome</subject><issn>1221-9118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kD1PwzAURT2AaAWd2ZBHlrR-dho7bCHlSyoCQffIebFpUFMHOxHqvyfQ0rs86eq8OxxCLoFNOSQQz3Bd-95_1HrK5VyekDFwDlEKoEZkEsInG5Iwzpg4IyORsDgFpsbkdtG7ymxdq7foje4Mdq7ZUes8fV1kOc1CcFgPfUW_625Nn7Pl-w3NaK6DoW-mdb67IKdWb4KZHO45Wd3frfLHaPny8JRnywiFUF0k5RwZJKLSJZq0TDgTyto5WkC0KEAkqpRKoEoMVzEASllaVsZSgC3jSpyT6_1s691Xb0JXNHVAs9norXF9KLhkqYxFDGxAZ3sUvQvBG1u0vm603xXAij9dxVFX8atr-Lg6jPdlY6oj_y9K_AD56miJ</recordid><startdate>20220701</startdate><enddate>20220701</enddate><creator>Moiş, Emil</creator><creator>Pop, Cristina Paula</creator><creator>Graur, Florin</creator><creator>Moldovan, Septimiu</creator><creator>Puia, Ion Cosmin</creator><creator>Zdrehuş, Claudiu</creator><creator>Mureşan, Ioan</creator><creator>Hajjar, Nadim Al</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20220701</creationdate><title>Duodenopancreatectomy for PDAC Associated with MALS: A Case Report</title><author>Moiş, Emil ; Pop, Cristina Paula ; Graur, Florin ; Moldovan, Septimiu ; Puia, Ion Cosmin ; Zdrehuş, Claudiu ; Mureşan, Ioan ; Hajjar, Nadim Al</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-775c0163dabce9b62038ff5cf1ccfc31368b783c86e28411c77bf0b4731fb4d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Aged</topic><topic>Carcinoma, Pancreatic Ductal - surgery</topic><topic>Constriction, Pathologic - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Median Arcuate Ligament Syndrome - complications</topic><topic>Median Arcuate Ligament Syndrome - diagnosis</topic><topic>Median Arcuate Ligament Syndrome - surgery</topic><topic>Pancreatic Neoplasms</topic><topic>Pancreatic Neoplasms - complications</topic><topic>Pancreatic Neoplasms - surgery</topic><topic>Pancreaticoduodenectomy - adverse effects</topic><topic>Treatment Outcome</topic><toplevel>online_resources</toplevel><creatorcontrib>Moiş, Emil</creatorcontrib><creatorcontrib>Pop, Cristina Paula</creatorcontrib><creatorcontrib>Graur, Florin</creatorcontrib><creatorcontrib>Moldovan, Septimiu</creatorcontrib><creatorcontrib>Puia, Ion Cosmin</creatorcontrib><creatorcontrib>Zdrehuş, Claudiu</creatorcontrib><creatorcontrib>Mureşan, Ioan</creatorcontrib><creatorcontrib>Hajjar, Nadim Al</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chirurgia (Bucharest, Romania : 1990)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moiş, Emil</au><au>Pop, Cristina Paula</au><au>Graur, Florin</au><au>Moldovan, Septimiu</au><au>Puia, Ion Cosmin</au><au>Zdrehuş, Claudiu</au><au>Mureşan, Ioan</au><au>Hajjar, Nadim Al</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Duodenopancreatectomy for PDAC Associated with MALS: A Case Report</atitle><jtitle>Chirurgia (Bucharest, Romania : 1990)</jtitle><addtitle>Chirurgia (Bucur)</addtitle><date>2022-07-01</date><risdate>2022</risdate><volume>117</volume><issue>4</issue><spage>493</spage><epage>498</epage><pages>493-498</pages><issn>1221-9118</issn><abstract>Pancreatic ductal adenocarcinoma (PDAC) is an aggressive form of pancreatic malignancy which occurs in over 90% of such cases. Pancreaticoduodenectomy (PD) is used with a curative purpose for localized PDAC. Case presentation: A 68-year-old woman presented to our service through a transfer from another service, to be investigated and treated for a head of the pancreas tumor in a tertiary referral hospital. After a complete clinical and paraclinical evaluation, the patient was diagnosed with a PDAC and also with a median arcuate ligament syndrome (MALS). The surgical treatment was considered adequate, therefore, the patient underwent a PD with transmesocolic hepaticojejunostomy, pancreaticogastric anastomosis, precolic end-to-side gastrojejunostomy, Witzel jejunostomy and with the help of the cardiovascular surgery team from the Heart Institute, Cluj- Napoca, an aortohepatic bypass using saphenous vein graft was performed. Conclusion: Bypass was essential because the blood flow in the proper hepatic artery was not restored after sectioning the median arcuate ligament and clamping the gastroduodenal artery. The patient had a favorable outcome. The particularity of the present case consists of the complete occlusion of the celiac trunk by MALS and the total vascularization of the supramesocolic organs due to the superior mesenteric artery through the gastroduodenal artery.</abstract><cop>Romania</cop><pmid>36049108</pmid><doi>10.21614/chirurgia.2757</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Carcinoma, Pancreatic Ductal - surgery Constriction, Pathologic - surgery Female Humans Median Arcuate Ligament Syndrome - complications Median Arcuate Ligament Syndrome - diagnosis Median Arcuate Ligament Syndrome - surgery Pancreatic Neoplasms Pancreatic Neoplasms - complications Pancreatic Neoplasms - surgery Pancreaticoduodenectomy - adverse effects Treatment Outcome |
title | Duodenopancreatectomy for PDAC Associated with MALS: A Case Report |
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