MRI: Evaluating the Application of FOCUS‐MUSE Diffusion‐Weighted Imaging in the Pancreas in Comparison With FOCUS, MUSE, and Single‐Shot DWIs

Background Diffusion‐weighted imaging (DWI) is a useful technique to detect pancreatic lesion. In DWIs, field‐of‐view optimized and constrained undistorted single‐shot (FOCUS) can improve the spatial resolution and multiplexed sensitivity‐encoding (MUSE) can gain a high signal‐to‐noise ratio (SNR)....

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Veröffentlicht in:Journal of magnetic resonance imaging 2023-04, Vol.57 (4), p.1156-1171
Hauptverfasser: Bai, Yu, Pei, Yigang, Liu, Weiyin Vivian, Liu, Wenguang, Xie, Simin, Wang, Xiao, Zhong, Linhui, Chen, Juan, Zhang, Lijuan, Masokano, Ismail Bilal, Li, Wenzheng
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container_end_page 1171
container_issue 4
container_start_page 1156
container_title Journal of magnetic resonance imaging
container_volume 57
creator Bai, Yu
Pei, Yigang
Liu, Weiyin Vivian
Liu, Wenguang
Xie, Simin
Wang, Xiao
Zhong, Linhui
Chen, Juan
Zhang, Lijuan
Masokano, Ismail Bilal
Li, Wenzheng
description Background Diffusion‐weighted imaging (DWI) is a useful technique to detect pancreatic lesion. In DWIs, field‐of‐view optimized and constrained undistorted single‐shot (FOCUS) can improve the spatial resolution and multiplexed sensitivity‐encoding (MUSE) can gain a high signal‐to‐noise ratio (SNR). Based on the advantage of FOCUS and MUSE, a new DWI sequence—named FOCUS‐MUSE DWI (FOCUS combined with MUSE)—was developed to delineate the pancreas. Purpose To investigate the reliability of FOCUS‐MUSE DWI compared to FOCUS, MUSE and single‐shot (SS) DWI via the systematical evaluation of the apparent diffusion coefficient (ADC) measurements, SNR and image quality. Study Type Prospective. Subjects A total of 33 healthy volunteers and 9 patients with pancreatic lesion. Field Strength/Sequence A 3.0 T scanner. FOCUS‐MUSE DWI, FOCUS DWI, MUSE DWI, SS DWI. Assessment For volunteers, ADC and SNR were measured by two readers in the pancreatic head, body, and tail. For all subjects, the diagnostic image quality score was assessed by three other readers on above four DWIs. Statistical Tests Paired‐sample T‐test, intraclass correlation (ICC), Bland–Altman method, Friedman test, Dunn‐Bonferroni post hoc test and kappa coefficient. A significance level of 0.05 was used. Results FOCUS‐MUSE DWI had the best intersession repeatability of ADC measurements (head: 59.53, body: 101.64, tail: 42.30) among the four DWIs, and also maintained the significantly highest SNR (reader 1 [head: 19.68 ± 3.23, body: 23.42 ± 5.00, tail: 28.85 ± 4.96], reader 2 [head: 19.93 ± 3.52, body: 23.02 ± 5.69, tail: 29.77 ± 6.33]) except for MUSE DWI. Furthermore, it significantly achieved better image quality in volunteers (median value: 4 score) and 9 patients (most in 4 score). Data Conclusion FOCUS‐MUSE DWI improved the reliability of pancreatic images with the most stable ADC measurement, best image quality score and sufficient SNR among four DWIs. Evidence Level 2 Technical Efficacy Stage 2
doi_str_mv 10.1002/jmri.28382
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In DWIs, field‐of‐view optimized and constrained undistorted single‐shot (FOCUS) can improve the spatial resolution and multiplexed sensitivity‐encoding (MUSE) can gain a high signal‐to‐noise ratio (SNR). Based on the advantage of FOCUS and MUSE, a new DWI sequence—named FOCUS‐MUSE DWI (FOCUS combined with MUSE)—was developed to delineate the pancreas. Purpose To investigate the reliability of FOCUS‐MUSE DWI compared to FOCUS, MUSE and single‐shot (SS) DWI via the systematical evaluation of the apparent diffusion coefficient (ADC) measurements, SNR and image quality. Study Type Prospective. Subjects A total of 33 healthy volunteers and 9 patients with pancreatic lesion. Field Strength/Sequence A 3.0 T scanner. FOCUS‐MUSE DWI, FOCUS DWI, MUSE DWI, SS DWI. Assessment For volunteers, ADC and SNR were measured by two readers in the pancreatic head, body, and tail. For all subjects, the diagnostic image quality score was assessed by three other readers on above four DWIs. Statistical Tests Paired‐sample T‐test, intraclass correlation (ICC), Bland–Altman method, Friedman test, Dunn‐Bonferroni post hoc test and kappa coefficient. A significance level of 0.05 was used. Results FOCUS‐MUSE DWI had the best intersession repeatability of ADC measurements (head: 59.53, body: 101.64, tail: 42.30) among the four DWIs, and also maintained the significantly highest SNR (reader 1 [head: 19.68 ± 3.23, body: 23.42 ± 5.00, tail: 28.85 ± 4.96], reader 2 [head: 19.93 ± 3.52, body: 23.02 ± 5.69, tail: 29.77 ± 6.33]) except for MUSE DWI. Furthermore, it significantly achieved better image quality in volunteers (median value: 4 score) and 9 patients (most in 4 score). Data Conclusion FOCUS‐MUSE DWI improved the reliability of pancreatic images with the most stable ADC measurement, best image quality score and sufficient SNR among four DWIs. Evidence Level 2 Technical Efficacy Stage 2</description><identifier>ISSN: 1053-1807</identifier><identifier>EISSN: 1522-2586</identifier><identifier>DOI: 10.1002/jmri.28382</identifier><identifier>PMID: 36053895</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley &amp; Sons, Inc</publisher><subject>Alprostadil ; Body measurements ; clinical application ; Diffusion coefficient ; Diffusion Magnetic Resonance Imaging - methods ; Echo-Planar Imaging - methods ; Evaluation ; Field strength ; FOCUS‐MUSE DWI ; Humans ; Image quality ; Lesions ; Magnetic Resonance Imaging ; Medical imaging ; Pancreas ; pancreatic DWIs ; Pancreatic Neoplasms ; Prospective Studies ; Quality assessment ; Reliability ; Reproducibility of Results ; Spatial discrimination ; Spatial resolution ; Statistical analysis ; Statistical tests ; Tails</subject><ispartof>Journal of magnetic resonance imaging, 2023-04, Vol.57 (4), p.1156-1171</ispartof><rights>2022 International Society for Magnetic Resonance in Medicine.</rights><rights>2023 International Society for Magnetic Resonance in Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3572-b3c9c0b8cf00a5bbda02a543a52580821a29024710271e70de060fd6b4dac20c3</citedby><cites>FETCH-LOGICAL-c3572-b3c9c0b8cf00a5bbda02a543a52580821a29024710271e70de060fd6b4dac20c3</cites><orcidid>0000-0003-1791-0097 ; 0000-0001-6841-3512 ; 0000-0002-7917-7612</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjmri.28382$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjmri.28382$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36053895$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bai, Yu</creatorcontrib><creatorcontrib>Pei, Yigang</creatorcontrib><creatorcontrib>Liu, Weiyin Vivian</creatorcontrib><creatorcontrib>Liu, Wenguang</creatorcontrib><creatorcontrib>Xie, Simin</creatorcontrib><creatorcontrib>Wang, Xiao</creatorcontrib><creatorcontrib>Zhong, Linhui</creatorcontrib><creatorcontrib>Chen, Juan</creatorcontrib><creatorcontrib>Zhang, Lijuan</creatorcontrib><creatorcontrib>Masokano, Ismail Bilal</creatorcontrib><creatorcontrib>Li, Wenzheng</creatorcontrib><title>MRI: Evaluating the Application of FOCUS‐MUSE Diffusion‐Weighted Imaging in the Pancreas in Comparison With FOCUS, MUSE, and Single‐Shot DWIs</title><title>Journal of magnetic resonance imaging</title><addtitle>J Magn Reson Imaging</addtitle><description>Background Diffusion‐weighted imaging (DWI) is a useful technique to detect pancreatic lesion. In DWIs, field‐of‐view optimized and constrained undistorted single‐shot (FOCUS) can improve the spatial resolution and multiplexed sensitivity‐encoding (MUSE) can gain a high signal‐to‐noise ratio (SNR). Based on the advantage of FOCUS and MUSE, a new DWI sequence—named FOCUS‐MUSE DWI (FOCUS combined with MUSE)—was developed to delineate the pancreas. Purpose To investigate the reliability of FOCUS‐MUSE DWI compared to FOCUS, MUSE and single‐shot (SS) DWI via the systematical evaluation of the apparent diffusion coefficient (ADC) measurements, SNR and image quality. Study Type Prospective. Subjects A total of 33 healthy volunteers and 9 patients with pancreatic lesion. Field Strength/Sequence A 3.0 T scanner. FOCUS‐MUSE DWI, FOCUS DWI, MUSE DWI, SS DWI. Assessment For volunteers, ADC and SNR were measured by two readers in the pancreatic head, body, and tail. For all subjects, the diagnostic image quality score was assessed by three other readers on above four DWIs. Statistical Tests Paired‐sample T‐test, intraclass correlation (ICC), Bland–Altman method, Friedman test, Dunn‐Bonferroni post hoc test and kappa coefficient. A significance level of 0.05 was used. Results FOCUS‐MUSE DWI had the best intersession repeatability of ADC measurements (head: 59.53, body: 101.64, tail: 42.30) among the four DWIs, and also maintained the significantly highest SNR (reader 1 [head: 19.68 ± 3.23, body: 23.42 ± 5.00, tail: 28.85 ± 4.96], reader 2 [head: 19.93 ± 3.52, body: 23.02 ± 5.69, tail: 29.77 ± 6.33]) except for MUSE DWI. Furthermore, it significantly achieved better image quality in volunteers (median value: 4 score) and 9 patients (most in 4 score). Data Conclusion FOCUS‐MUSE DWI improved the reliability of pancreatic images with the most stable ADC measurement, best image quality score and sufficient SNR among four DWIs. 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Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of magnetic resonance imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bai, Yu</au><au>Pei, Yigang</au><au>Liu, Weiyin Vivian</au><au>Liu, Wenguang</au><au>Xie, Simin</au><au>Wang, Xiao</au><au>Zhong, Linhui</au><au>Chen, Juan</au><au>Zhang, Lijuan</au><au>Masokano, Ismail Bilal</au><au>Li, Wenzheng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MRI: Evaluating the Application of FOCUS‐MUSE Diffusion‐Weighted Imaging in the Pancreas in Comparison With FOCUS, MUSE, and Single‐Shot DWIs</atitle><jtitle>Journal of magnetic resonance imaging</jtitle><addtitle>J Magn Reson Imaging</addtitle><date>2023-04</date><risdate>2023</risdate><volume>57</volume><issue>4</issue><spage>1156</spage><epage>1171</epage><pages>1156-1171</pages><issn>1053-1807</issn><eissn>1522-2586</eissn><abstract>Background Diffusion‐weighted imaging (DWI) is a useful technique to detect pancreatic lesion. In DWIs, field‐of‐view optimized and constrained undistorted single‐shot (FOCUS) can improve the spatial resolution and multiplexed sensitivity‐encoding (MUSE) can gain a high signal‐to‐noise ratio (SNR). Based on the advantage of FOCUS and MUSE, a new DWI sequence—named FOCUS‐MUSE DWI (FOCUS combined with MUSE)—was developed to delineate the pancreas. Purpose To investigate the reliability of FOCUS‐MUSE DWI compared to FOCUS, MUSE and single‐shot (SS) DWI via the systematical evaluation of the apparent diffusion coefficient (ADC) measurements, SNR and image quality. Study Type Prospective. Subjects A total of 33 healthy volunteers and 9 patients with pancreatic lesion. Field Strength/Sequence A 3.0 T scanner. FOCUS‐MUSE DWI, FOCUS DWI, MUSE DWI, SS DWI. Assessment For volunteers, ADC and SNR were measured by two readers in the pancreatic head, body, and tail. For all subjects, the diagnostic image quality score was assessed by three other readers on above four DWIs. Statistical Tests Paired‐sample T‐test, intraclass correlation (ICC), Bland–Altman method, Friedman test, Dunn‐Bonferroni post hoc test and kappa coefficient. A significance level of 0.05 was used. Results FOCUS‐MUSE DWI had the best intersession repeatability of ADC measurements (head: 59.53, body: 101.64, tail: 42.30) among the four DWIs, and also maintained the significantly highest SNR (reader 1 [head: 19.68 ± 3.23, body: 23.42 ± 5.00, tail: 28.85 ± 4.96], reader 2 [head: 19.93 ± 3.52, body: 23.02 ± 5.69, tail: 29.77 ± 6.33]) except for MUSE DWI. Furthermore, it significantly achieved better image quality in volunteers (median value: 4 score) and 9 patients (most in 4 score). Data Conclusion FOCUS‐MUSE DWI improved the reliability of pancreatic images with the most stable ADC measurement, best image quality score and sufficient SNR among four DWIs. Evidence Level 2 Technical Efficacy Stage 2</abstract><cop>Hoboken, USA</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>36053895</pmid><doi>10.1002/jmri.28382</doi><tpages>16</tpages><orcidid>https://orcid.org/0000-0003-1791-0097</orcidid><orcidid>https://orcid.org/0000-0001-6841-3512</orcidid><orcidid>https://orcid.org/0000-0002-7917-7612</orcidid></addata></record>
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Alprostadil
Body measurements
clinical application
Diffusion coefficient
Diffusion Magnetic Resonance Imaging - methods
Echo-Planar Imaging - methods
Evaluation
Field strength
FOCUS‐MUSE DWI
Humans
Image quality
Lesions
Magnetic Resonance Imaging
Medical imaging
Pancreas
pancreatic DWIs
Pancreatic Neoplasms
Prospective Studies
Quality assessment
Reliability
Reproducibility of Results
Spatial discrimination
Spatial resolution
Statistical analysis
Statistical tests
Tails
title MRI: Evaluating the Application of FOCUS‐MUSE Diffusion‐Weighted Imaging in the Pancreas in Comparison With FOCUS, MUSE, and Single‐Shot DWIs
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