Memory trace imbalance in reinforcement and punishment systems can reinforce implicit choices leading to obsessive-compulsive behavior

We may view most of our daily activities as rational action selections; however, we sometimes reinforce maladaptive behaviors despite having explicit environmental knowledge. In this study, we model obsessive-compulsive disorder (OCD) symptoms as implicitly learned maladaptive behaviors. Simulations...

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Veröffentlicht in:	Cell reports (Cambridge) 2022-08, Vol.40 (9), p.111275-111275, Article 111275
Hauptverfasser:	Sakai, Yuki, Sakai, Yutaka, Abe, Yoshinari, Narumoto, Jin, Tanaka, Saori C.
Format:	Artikel
Sprache:	eng
Schlagworte:	behavioral therapy computational model credit assignment decision making eligibility trace memory trace obsessive-compulsive disorder prediction error reinforcement learning serotonin reuptake inhibitor
Online-Zugang:	Volltext
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