A bovine milk-derived peptide ameliorates alloxan-injured pancreatic β cells through IRS2/PI3K/Akt signaling

Lacto-ghrestatin is abovine milk-derived peptide with the sequence of LIVTQTMKG, named LGP9 here. This study aimed to investigate protective effects of LGP9 on diabetic β cells in vivo and in vitro. Type-1-diabetic (T1D) mice were generated by alloxan (ALX; 50 mg/kg, i.v.) and received a four-week t...

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Veröffentlicht in:	Life sciences (1973) 2022-11, Vol.308, p.120907-120907, Article 120907
Hauptverfasser:	Huang, Rongrong, Lu, Yunbiao, Xie, Zhifei, Yang, Xuegan, Ou, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt Alloxan LGP9 PI3K Type-1-diabetic mice
Online-Zugang:	Volltext
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