Reduced PTCH2 expression is associated with glioma development through its regulation of the PTEN/AKT signaling pathway

Mutations in the human protein patched homolog (PTCH) gene have been demonstrated to be associated with cancer development in several types of malignancy. However, the underlying mechanism of PTCH-associated cancer development remains poorly understood, to the best of our knowledge. In the present s...

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Veröffentlicht in:	Biochemical and biophysical research communications 2022-10, Vol.627, p.76-83
Hauptverfasser:	Han, Jizhong, Deng, Huajiang, Xiong, Yu, Xia, Xiangguo, Bao, Changshun, Chen, Ligang, Zhao, Qin, Zhong, Shunjie, Peng, Lilei, Zhong, Chuanhong
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT Glioma PTCH2 PTEN
Online-Zugang:	Volltext
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