Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity‐related cancer risk and mortality in Black and Latina Women's Health Initiative participants
Background Although adherence to the American Cancer Society (ACS) Guidelines on Nutrition and Physical Activity for Cancer Prevention associates with lower risk of obesity‐related cancer (ORC) incidence and mortality, evidence in Black and Latina women is limited. This association was examined in B...
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| Veröffentlicht in: | Cancer 2022-10, Vol.128 (20), p.3630-3640 |
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| creator | Pichardo, Margaret S. Esserman, Denise Ferrucci, Leah M. Molina, Yamile Chlebowski, Rowan T. Pan, Kathy Garcia, David O. Lane, Dorothy S. Shadyab, Aladdin H. Lopez‐Pentecost, Melissa Luo, Juhua Kato, Ikuko Springfield, Sparkle Rosal, Milagros C. Bea, Jennifer W. Cespedes Feliciano, Elizabeth M. Qi, Lihong Nassir, Rami Snetselaar, Linda Manson, JoAnn Bird, Chloe Irwin, Melinda L. |
| description | Background
Although adherence to the American Cancer Society (ACS) Guidelines on Nutrition and Physical Activity for Cancer Prevention associates with lower risk of obesity‐related cancer (ORC) incidence and mortality, evidence in Black and Latina women is limited. This association was examined in Black and Latina participants in the Women's Health Initiative (WHI).
Methods
Semi‐Markov multistate model examined the association between ACS guideline adherence and ORC incidence and mortality in the presence of competing events, combined and separately, for 9301 Black and 4221 Latina postmenopausal women. Additionally, ACS guideline adherence was examined in a subset of less common ORCs and potential effect modification by neighborhood socioeconomic status and smoking.
Results
Over a median of 11.1, 12.5, and 3.7 years of follow‐up for incidence, nonconditional mortality, and conditional mortality, respectively, 1191 ORCs (Black/Latina women: 841/269), 1970 all‐cause deaths (Black/Latina women: 1576/394), and 341 ORC‐related deaths (Black/Latina women: 259/82) were observed. Higher ACS guideline adherence was associated with lower ORC incidence for both Black (cause‐specific hazard ratio [CSHR]highvs.low: 0.72; 95% CI, 0.55–0.94) and Latina (CSHRhighvs.low: 0.58, 95% CI, 0.36–0.93) women; but not conditional all‐cause mortality (Black hazard ratio [HR]highvs.low: 0.86; 95% CI, 0.53–1.39; Latina HRhighvs.low: 0.81; 95% CI, 0.32–2.06). Higher adherence was associated with lower incidence of less common ORC (Ptrend = .025), but conditional mortality events were limited. Adherence and ORC‐specific deaths were not associated and there was no evidence of effect modification.
Conclusions
Adherence to the ACS guidelines was associated with lower risk of ORCs and less common ORCs but was not for conditional ORC‐related mortality.
Lay summary
Evidence on the association between the American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention and cancer remains scarce for women of color.
Adherence to the guidelines and risk of developing one of 13 obesity‐related cancers among Black and Latina women in the Women's Health Initiative was examined. Women who followed the lifestyle guidelines had 28% to 42% lower risk of obesity‐related cancer.
These findings support public health interventions to reduce growing racial/ethnic disparities in obesity‐related cancers.
Black and Latina women who followed the American Cancer Society guidelines on n |
| doi_str_mv | 10.1002/cncr.34428 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2705750660</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2717599932</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3578-3413fb7fa49516ae68c9132f8838ea3988612730a084e62cd78d3271999aaec73</originalsourceid><addsrcrecordid>eNp90ctu1DAUBuAIgei0sOEBkCUWVEhT7DiJneUQQVtpBBIXwS4645xoXBw7tZ1Bs-MReDv2PAmepu2CBSvfPv-y_GfZM0bPGKX5a2WVP-NFkcsH2YLRWiwpK_KH2YJSKpdlwb8dZcchXKWlyEv-ODviZV1XsmKL7Peq26JHq5BER-IWyWpArxVY0kDa9eSTUxrjnpxPukOjLQbiLLFT9DrqNAPbkXG7D-mOIaCi3umke-eJmgNGjzu099ZtMCTx5-cvjwYidnfO6_D9RgzORzCHFG3JGwNq3l5D1BbIVzegfRnIBYKJW3Jp0zPSyQ7JCD5qpUewMTzJHvVgAj69HU-yL-_efm4ulusP55fNar1UvBRyyQvG-43ooahLVgFWUtWM572UXCLwWqZPygWnQGWBVa46ITueC1bXNQAqwU-y0zl39O56whDbQQeFxoBFN4U2F7QUJa0qmuiLf-iVm7xNr0uKiVRJzfOkXs1KeReCx74dvR7A71tG20Pd7aHu9qbuhJ_fRk6bAbt7etdvAmwGP7TB_X-i2uZ983EO_QseSLnm</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2717599932</pqid></control><display><type>article</type><title>Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity‐related cancer risk and mortality in Black and Latina Women's Health Initiative participants</title><source>Wiley Free Content</source><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Pichardo, Margaret S. ; Esserman, Denise ; Ferrucci, Leah M. ; Molina, Yamile ; Chlebowski, Rowan T. ; Pan, Kathy ; Garcia, David O. ; Lane, Dorothy S. ; Shadyab, Aladdin H. ; Lopez‐Pentecost, Melissa ; Luo, Juhua ; Kato, Ikuko ; Springfield, Sparkle ; Rosal, Milagros C. ; Bea, Jennifer W. ; Cespedes Feliciano, Elizabeth M. ; Qi, Lihong ; Nassir, Rami ; Snetselaar, Linda ; Manson, JoAnn ; Bird, Chloe ; Irwin, Melinda L.</creator><creatorcontrib>Pichardo, Margaret S. ; Esserman, Denise ; Ferrucci, Leah M. ; Molina, Yamile ; Chlebowski, Rowan T. ; Pan, Kathy ; Garcia, David O. ; Lane, Dorothy S. ; Shadyab, Aladdin H. ; Lopez‐Pentecost, Melissa ; Luo, Juhua ; Kato, Ikuko ; Springfield, Sparkle ; Rosal, Milagros C. ; Bea, Jennifer W. ; Cespedes Feliciano, Elizabeth M. ; Qi, Lihong ; Nassir, Rami ; Snetselaar, Linda ; Manson, JoAnn ; Bird, Chloe ; Irwin, Melinda L.</creatorcontrib><description>Background
Although adherence to the American Cancer Society (ACS) Guidelines on Nutrition and Physical Activity for Cancer Prevention associates with lower risk of obesity‐related cancer (ORC) incidence and mortality, evidence in Black and Latina women is limited. This association was examined in Black and Latina participants in the Women's Health Initiative (WHI).
Methods
Semi‐Markov multistate model examined the association between ACS guideline adherence and ORC incidence and mortality in the presence of competing events, combined and separately, for 9301 Black and 4221 Latina postmenopausal women. Additionally, ACS guideline adherence was examined in a subset of less common ORCs and potential effect modification by neighborhood socioeconomic status and smoking.
Results
Over a median of 11.1, 12.5, and 3.7 years of follow‐up for incidence, nonconditional mortality, and conditional mortality, respectively, 1191 ORCs (Black/Latina women: 841/269), 1970 all‐cause deaths (Black/Latina women: 1576/394), and 341 ORC‐related deaths (Black/Latina women: 259/82) were observed. Higher ACS guideline adherence was associated with lower ORC incidence for both Black (cause‐specific hazard ratio [CSHR]highvs.low: 0.72; 95% CI, 0.55–0.94) and Latina (CSHRhighvs.low: 0.58, 95% CI, 0.36–0.93) women; but not conditional all‐cause mortality (Black hazard ratio [HR]highvs.low: 0.86; 95% CI, 0.53–1.39; Latina HRhighvs.low: 0.81; 95% CI, 0.32–2.06). Higher adherence was associated with lower incidence of less common ORC (Ptrend = .025), but conditional mortality events were limited. Adherence and ORC‐specific deaths were not associated and there was no evidence of effect modification.
Conclusions
Adherence to the ACS guidelines was associated with lower risk of ORCs and less common ORCs but was not for conditional ORC‐related mortality.
Lay summary
Evidence on the association between the American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention and cancer remains scarce for women of color.
Adherence to the guidelines and risk of developing one of 13 obesity‐related cancers among Black and Latina women in the Women's Health Initiative was examined. Women who followed the lifestyle guidelines had 28% to 42% lower risk of obesity‐related cancer.
These findings support public health interventions to reduce growing racial/ethnic disparities in obesity‐related cancers.
Black and Latina women who followed the American Cancer Society guidelines on nutrition and physical activity for cancer prevention experienced lower incidence of obesity related cancers. These findings support public health education and interventions to reduce growing racial/ethnic disparities in incidence of obesity‐related cancers.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/cncr.34428</identifier><identifier>PMID: 35996861</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>American Cancer Society ; Black/African American ; Cancer ; cancer risk ; Disease prevention ; Exercise ; Fatalities ; Female ; Guidelines ; Health hazards ; Health risks ; Hispanic or Latino ; Hispanic/Latina ; Humans ; lifestyle guidelines ; Mortality ; Neoplasms - epidemiology ; Neoplasms - prevention & control ; Nutrition ; Obesity ; Obesity - complications ; Obesity - epidemiology ; Oncology ; Physical activity ; Post-menopause ; Prevention ; Public health ; Risk ; Risk Factors ; Socioeconomics ; United States - epidemiology ; Women's Health ; Womens health</subject><ispartof>Cancer, 2022-10, Vol.128 (20), p.3630-3640</ispartof><rights>2022 American Cancer Society.</rights><rights>2022 American Cancer Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3578-3413fb7fa49516ae68c9132f8838ea3988612730a084e62cd78d3271999aaec73</citedby><cites>FETCH-LOGICAL-c3578-3413fb7fa49516ae68c9132f8838ea3988612730a084e62cd78d3271999aaec73</cites><orcidid>0000-0001-8742-5658 ; 0000-0002-8901-4462 ; 0000-0002-9132-4400 ; 0000-0003-1192-4017</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fcncr.34428$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fcncr.34428$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,1427,27903,27904,45553,45554,46387,46811</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35996861$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pichardo, Margaret S.</creatorcontrib><creatorcontrib>Esserman, Denise</creatorcontrib><creatorcontrib>Ferrucci, Leah M.</creatorcontrib><creatorcontrib>Molina, Yamile</creatorcontrib><creatorcontrib>Chlebowski, Rowan T.</creatorcontrib><creatorcontrib>Pan, Kathy</creatorcontrib><creatorcontrib>Garcia, David O.</creatorcontrib><creatorcontrib>Lane, Dorothy S.</creatorcontrib><creatorcontrib>Shadyab, Aladdin H.</creatorcontrib><creatorcontrib>Lopez‐Pentecost, Melissa</creatorcontrib><creatorcontrib>Luo, Juhua</creatorcontrib><creatorcontrib>Kato, Ikuko</creatorcontrib><creatorcontrib>Springfield, Sparkle</creatorcontrib><creatorcontrib>Rosal, Milagros C.</creatorcontrib><creatorcontrib>Bea, Jennifer W.</creatorcontrib><creatorcontrib>Cespedes Feliciano, Elizabeth M.</creatorcontrib><creatorcontrib>Qi, Lihong</creatorcontrib><creatorcontrib>Nassir, Rami</creatorcontrib><creatorcontrib>Snetselaar, Linda</creatorcontrib><creatorcontrib>Manson, JoAnn</creatorcontrib><creatorcontrib>Bird, Chloe</creatorcontrib><creatorcontrib>Irwin, Melinda L.</creatorcontrib><title>Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity‐related cancer risk and mortality in Black and Latina Women's Health Initiative participants</title><title>Cancer</title><addtitle>Cancer</addtitle><description>Background
Although adherence to the American Cancer Society (ACS) Guidelines on Nutrition and Physical Activity for Cancer Prevention associates with lower risk of obesity‐related cancer (ORC) incidence and mortality, evidence in Black and Latina women is limited. This association was examined in Black and Latina participants in the Women's Health Initiative (WHI).
Methods
Semi‐Markov multistate model examined the association between ACS guideline adherence and ORC incidence and mortality in the presence of competing events, combined and separately, for 9301 Black and 4221 Latina postmenopausal women. Additionally, ACS guideline adherence was examined in a subset of less common ORCs and potential effect modification by neighborhood socioeconomic status and smoking.
Results
Over a median of 11.1, 12.5, and 3.7 years of follow‐up for incidence, nonconditional mortality, and conditional mortality, respectively, 1191 ORCs (Black/Latina women: 841/269), 1970 all‐cause deaths (Black/Latina women: 1576/394), and 341 ORC‐related deaths (Black/Latina women: 259/82) were observed. Higher ACS guideline adherence was associated with lower ORC incidence for both Black (cause‐specific hazard ratio [CSHR]highvs.low: 0.72; 95% CI, 0.55–0.94) and Latina (CSHRhighvs.low: 0.58, 95% CI, 0.36–0.93) women; but not conditional all‐cause mortality (Black hazard ratio [HR]highvs.low: 0.86; 95% CI, 0.53–1.39; Latina HRhighvs.low: 0.81; 95% CI, 0.32–2.06). Higher adherence was associated with lower incidence of less common ORC (Ptrend = .025), but conditional mortality events were limited. Adherence and ORC‐specific deaths were not associated and there was no evidence of effect modification.
Conclusions
Adherence to the ACS guidelines was associated with lower risk of ORCs and less common ORCs but was not for conditional ORC‐related mortality.
Lay summary
Evidence on the association between the American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention and cancer remains scarce for women of color.
Adherence to the guidelines and risk of developing one of 13 obesity‐related cancers among Black and Latina women in the Women's Health Initiative was examined. Women who followed the lifestyle guidelines had 28% to 42% lower risk of obesity‐related cancer.
These findings support public health interventions to reduce growing racial/ethnic disparities in obesity‐related cancers.
Black and Latina women who followed the American Cancer Society guidelines on nutrition and physical activity for cancer prevention experienced lower incidence of obesity related cancers. These findings support public health education and interventions to reduce growing racial/ethnic disparities in incidence of obesity‐related cancers.</description><subject>American Cancer Society</subject><subject>Black/African American</subject><subject>Cancer</subject><subject>cancer risk</subject><subject>Disease prevention</subject><subject>Exercise</subject><subject>Fatalities</subject><subject>Female</subject><subject>Guidelines</subject><subject>Health hazards</subject><subject>Health risks</subject><subject>Hispanic or Latino</subject><subject>Hispanic/Latina</subject><subject>Humans</subject><subject>lifestyle guidelines</subject><subject>Mortality</subject><subject>Neoplasms - epidemiology</subject><subject>Neoplasms - prevention & control</subject><subject>Nutrition</subject><subject>Obesity</subject><subject>Obesity - complications</subject><subject>Obesity - epidemiology</subject><subject>Oncology</subject><subject>Physical activity</subject><subject>Post-menopause</subject><subject>Prevention</subject><subject>Public health</subject><subject>Risk</subject><subject>Risk Factors</subject><subject>Socioeconomics</subject><subject>United States - epidemiology</subject><subject>Women's Health</subject><subject>Womens health</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90ctu1DAUBuAIgei0sOEBkCUWVEhT7DiJneUQQVtpBBIXwS4645xoXBw7tZ1Bs-MReDv2PAmepu2CBSvfPv-y_GfZM0bPGKX5a2WVP-NFkcsH2YLRWiwpK_KH2YJSKpdlwb8dZcchXKWlyEv-ODviZV1XsmKL7Peq26JHq5BER-IWyWpArxVY0kDa9eSTUxrjnpxPukOjLQbiLLFT9DrqNAPbkXG7D-mOIaCi3umke-eJmgNGjzu099ZtMCTx5-cvjwYidnfO6_D9RgzORzCHFG3JGwNq3l5D1BbIVzegfRnIBYKJW3Jp0zPSyQ7JCD5qpUewMTzJHvVgAj69HU-yL-_efm4ulusP55fNar1UvBRyyQvG-43ooahLVgFWUtWM572UXCLwWqZPygWnQGWBVa46ITueC1bXNQAqwU-y0zl39O56whDbQQeFxoBFN4U2F7QUJa0qmuiLf-iVm7xNr0uKiVRJzfOkXs1KeReCx74dvR7A71tG20Pd7aHu9qbuhJ_fRk6bAbt7etdvAmwGP7TB_X-i2uZ983EO_QseSLnm</recordid><startdate>202210</startdate><enddate>202210</enddate><creator>Pichardo, Margaret S.</creator><creator>Esserman, Denise</creator><creator>Ferrucci, Leah M.</creator><creator>Molina, Yamile</creator><creator>Chlebowski, Rowan T.</creator><creator>Pan, Kathy</creator><creator>Garcia, David O.</creator><creator>Lane, Dorothy S.</creator><creator>Shadyab, Aladdin H.</creator><creator>Lopez‐Pentecost, Melissa</creator><creator>Luo, Juhua</creator><creator>Kato, Ikuko</creator><creator>Springfield, Sparkle</creator><creator>Rosal, Milagros C.</creator><creator>Bea, Jennifer W.</creator><creator>Cespedes Feliciano, Elizabeth M.</creator><creator>Qi, Lihong</creator><creator>Nassir, Rami</creator><creator>Snetselaar, Linda</creator><creator>Manson, JoAnn</creator><creator>Bird, Chloe</creator><creator>Irwin, Melinda L.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TO</scope><scope>7U7</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8742-5658</orcidid><orcidid>https://orcid.org/0000-0002-8901-4462</orcidid><orcidid>https://orcid.org/0000-0002-9132-4400</orcidid><orcidid>https://orcid.org/0000-0003-1192-4017</orcidid></search><sort><creationdate>202210</creationdate><title>Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity‐related cancer risk and mortality in Black and Latina Women's Health Initiative participants</title><author>Pichardo, Margaret S. ; Esserman, Denise ; Ferrucci, Leah M. ; Molina, Yamile ; Chlebowski, Rowan T. ; Pan, Kathy ; Garcia, David O. ; Lane, Dorothy S. ; Shadyab, Aladdin H. ; Lopez‐Pentecost, Melissa ; Luo, Juhua ; Kato, Ikuko ; Springfield, Sparkle ; Rosal, Milagros C. ; Bea, Jennifer W. ; Cespedes Feliciano, Elizabeth M. ; Qi, Lihong ; Nassir, Rami ; Snetselaar, Linda ; Manson, JoAnn ; Bird, Chloe ; Irwin, Melinda L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3578-3413fb7fa49516ae68c9132f8838ea3988612730a084e62cd78d3271999aaec73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>American Cancer Society</topic><topic>Black/African American</topic><topic>Cancer</topic><topic>cancer risk</topic><topic>Disease prevention</topic><topic>Exercise</topic><topic>Fatalities</topic><topic>Female</topic><topic>Guidelines</topic><topic>Health hazards</topic><topic>Health risks</topic><topic>Hispanic or Latino</topic><topic>Hispanic/Latina</topic><topic>Humans</topic><topic>lifestyle guidelines</topic><topic>Mortality</topic><topic>Neoplasms - epidemiology</topic><topic>Neoplasms - prevention & control</topic><topic>Nutrition</topic><topic>Obesity</topic><topic>Obesity - complications</topic><topic>Obesity - epidemiology</topic><topic>Oncology</topic><topic>Physical activity</topic><topic>Post-menopause</topic><topic>Prevention</topic><topic>Public health</topic><topic>Risk</topic><topic>Risk Factors</topic><topic>Socioeconomics</topic><topic>United States - epidemiology</topic><topic>Women's Health</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pichardo, Margaret S.</creatorcontrib><creatorcontrib>Esserman, Denise</creatorcontrib><creatorcontrib>Ferrucci, Leah M.</creatorcontrib><creatorcontrib>Molina, Yamile</creatorcontrib><creatorcontrib>Chlebowski, Rowan T.</creatorcontrib><creatorcontrib>Pan, Kathy</creatorcontrib><creatorcontrib>Garcia, David O.</creatorcontrib><creatorcontrib>Lane, Dorothy S.</creatorcontrib><creatorcontrib>Shadyab, Aladdin H.</creatorcontrib><creatorcontrib>Lopez‐Pentecost, Melissa</creatorcontrib><creatorcontrib>Luo, Juhua</creatorcontrib><creatorcontrib>Kato, Ikuko</creatorcontrib><creatorcontrib>Springfield, Sparkle</creatorcontrib><creatorcontrib>Rosal, Milagros C.</creatorcontrib><creatorcontrib>Bea, Jennifer W.</creatorcontrib><creatorcontrib>Cespedes Feliciano, Elizabeth M.</creatorcontrib><creatorcontrib>Qi, Lihong</creatorcontrib><creatorcontrib>Nassir, Rami</creatorcontrib><creatorcontrib>Snetselaar, Linda</creatorcontrib><creatorcontrib>Manson, JoAnn</creatorcontrib><creatorcontrib>Bird, Chloe</creatorcontrib><creatorcontrib>Irwin, Melinda L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pichardo, Margaret S.</au><au>Esserman, Denise</au><au>Ferrucci, Leah M.</au><au>Molina, Yamile</au><au>Chlebowski, Rowan T.</au><au>Pan, Kathy</au><au>Garcia, David O.</au><au>Lane, Dorothy S.</au><au>Shadyab, Aladdin H.</au><au>Lopez‐Pentecost, Melissa</au><au>Luo, Juhua</au><au>Kato, Ikuko</au><au>Springfield, Sparkle</au><au>Rosal, Milagros C.</au><au>Bea, Jennifer W.</au><au>Cespedes Feliciano, Elizabeth M.</au><au>Qi, Lihong</au><au>Nassir, Rami</au><au>Snetselaar, Linda</au><au>Manson, JoAnn</au><au>Bird, Chloe</au><au>Irwin, Melinda L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity‐related cancer risk and mortality in Black and Latina Women's Health Initiative participants</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>2022-10</date><risdate>2022</risdate><volume>128</volume><issue>20</issue><spage>3630</spage><epage>3640</epage><pages>3630-3640</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><abstract>Background
Although adherence to the American Cancer Society (ACS) Guidelines on Nutrition and Physical Activity for Cancer Prevention associates with lower risk of obesity‐related cancer (ORC) incidence and mortality, evidence in Black and Latina women is limited. This association was examined in Black and Latina participants in the Women's Health Initiative (WHI).
Methods
Semi‐Markov multistate model examined the association between ACS guideline adherence and ORC incidence and mortality in the presence of competing events, combined and separately, for 9301 Black and 4221 Latina postmenopausal women. Additionally, ACS guideline adherence was examined in a subset of less common ORCs and potential effect modification by neighborhood socioeconomic status and smoking.
Results
Over a median of 11.1, 12.5, and 3.7 years of follow‐up for incidence, nonconditional mortality, and conditional mortality, respectively, 1191 ORCs (Black/Latina women: 841/269), 1970 all‐cause deaths (Black/Latina women: 1576/394), and 341 ORC‐related deaths (Black/Latina women: 259/82) were observed. Higher ACS guideline adherence was associated with lower ORC incidence for both Black (cause‐specific hazard ratio [CSHR]highvs.low: 0.72; 95% CI, 0.55–0.94) and Latina (CSHRhighvs.low: 0.58, 95% CI, 0.36–0.93) women; but not conditional all‐cause mortality (Black hazard ratio [HR]highvs.low: 0.86; 95% CI, 0.53–1.39; Latina HRhighvs.low: 0.81; 95% CI, 0.32–2.06). Higher adherence was associated with lower incidence of less common ORC (Ptrend = .025), but conditional mortality events were limited. Adherence and ORC‐specific deaths were not associated and there was no evidence of effect modification.
Conclusions
Adherence to the ACS guidelines was associated with lower risk of ORCs and less common ORCs but was not for conditional ORC‐related mortality.
Lay summary
Evidence on the association between the American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention and cancer remains scarce for women of color.
Adherence to the guidelines and risk of developing one of 13 obesity‐related cancers among Black and Latina women in the Women's Health Initiative was examined. Women who followed the lifestyle guidelines had 28% to 42% lower risk of obesity‐related cancer.
These findings support public health interventions to reduce growing racial/ethnic disparities in obesity‐related cancers.
Black and Latina women who followed the American Cancer Society guidelines on nutrition and physical activity for cancer prevention experienced lower incidence of obesity related cancers. These findings support public health education and interventions to reduce growing racial/ethnic disparities in incidence of obesity‐related cancers.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>35996861</pmid><doi>10.1002/cncr.34428</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-8742-5658</orcidid><orcidid>https://orcid.org/0000-0002-8901-4462</orcidid><orcidid>https://orcid.org/0000-0002-9132-4400</orcidid><orcidid>https://orcid.org/0000-0003-1192-4017</orcidid></addata></record> |
| fulltext | fulltext |
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| ispartof | Cancer, 2022-10, Vol.128 (20), p.3630-3640 |
| issn | 0008-543X 1097-0142 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2705750660 |
| source | Wiley Free Content; MEDLINE; Wiley Online Library Journals Frontfile Complete; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | American Cancer Society Black/African American Cancer cancer risk Disease prevention Exercise Fatalities Female Guidelines Health hazards Health risks Hispanic or Latino Hispanic/Latina Humans lifestyle guidelines Mortality Neoplasms - epidemiology Neoplasms - prevention & control Nutrition Obesity Obesity - complications Obesity - epidemiology Oncology Physical activity Post-menopause Prevention Public health Risk Risk Factors Socioeconomics United States - epidemiology Women's Health Womens health |
| title | Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity‐related cancer risk and mortality in Black and Latina Women's Health Initiative participants |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T15%3A32%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Adherence%20to%20the%20American%20Cancer%20Society%20Guidelines%20on%20nutrition%20and%20physical%20activity%20for%20cancer%20prevention%20and%20obesity%E2%80%90related%20cancer%20risk%20and%20mortality%20in%20Black%20and%20Latina%20Women's%20Health%20Initiative%20participants&rft.jtitle=Cancer&rft.au=Pichardo,%20Margaret%20S.&rft.date=2022-10&rft.volume=128&rft.issue=20&rft.spage=3630&rft.epage=3640&rft.pages=3630-3640&rft.issn=0008-543X&rft.eissn=1097-0142&rft_id=info:doi/10.1002/cncr.34428&rft_dat=%3Cproquest_cross%3E2717599932%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2717599932&rft_id=info:pmid/35996861&rfr_iscdi=true |