Enzyme-responsive nano-drug delivery system for combined antitumor therapy

Efficient drug loading, tumor targeting, intratumoral penetration, and cellular uptake are the main factors affecting the effectiveness of drug delivery systems in oncotherapy. Based on the tumor microenvironment, we proposed to develop Curcumin (Cur)-loaded matrix metalloproteinase (MMP)-responsive...

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Veröffentlicht in:	International journal of biological macromolecules 2022-11, Vol.220, p.1133-1145
Hauptverfasser:	Guo, Fangyuan, Jiao, Yunlong, Du, Yinzhou, Luo, Shuai, Hong, Weiyong, Fu, Qiafan, Li, Aiqin, Wang, Guoping, Yang, Gensheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Combined antitumor therapy Curcumin-loaded MMP-responsive nanoparticles Losartan PEG-peptides Star-shaped polyester nanoparticles Tumor targeting
Online-Zugang:	Volltext
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