Meckel diverticulum in the pediatric population: Patient presentation and performance of imaging in prospective diagnosis

To determine the most common presentations of Meckel diverticulum (MD) in children and the performance of imaging modalities in prospective diagnosis. A 28-year retrospective review was performed of children under 18 years of age with MD listed as a diagnosis on pathology and/or surgical reports. Th...

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Veröffentlicht in:Clinical imaging 2022-11, Vol.91, p.37-44
Hauptverfasser: McDonald, Jennifer S., Horst, Kelly K., Thacker, Paul G., Thomas, Kristen B., Klinkner, Denise B., Kolbe, Amy B.
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container_end_page 44
container_issue
container_start_page 37
container_title Clinical imaging
container_volume 91
creator McDonald, Jennifer S.
Horst, Kelly K.
Thacker, Paul G.
Thomas, Kristen B.
Klinkner, Denise B.
Kolbe, Amy B.
description To determine the most common presentations of Meckel diverticulum (MD) in children and the performance of imaging modalities in prospective diagnosis. A 28-year retrospective review was performed of children under 18 years of age with MD listed as a diagnosis on pathology and/or surgical reports. The medical record was reviewed to determine presenting clinical scenarios. All imaging performed for each case was reviewed. Seventy-six patients met inclusion criteria. Of the surgically removed MD, most presented with abdominal symptoms (n = 31, 41%); gastrointestinal (GI) bleeding (n = 15, 20%), or both abdominal symptoms and GI bleeding (n = 7, 9%). Twenty-nine percent of MD were discovered incidentally at surgery performed for other reasons. Of the symptomatic MD, only 31% were prospectively diagnosed. For patients with abdominal symptoms, CT had a sensitivity of 13% (3/24) while nuclear medicine (NM) scan had a sensitivity of 0% (0/2). For patients with GI bleed, CT had a sensitivity of 29% (2/7) and NM scan had a sensitivity of 71% (10/14). For patients with both abdominal symptoms and GI bleed, CT was 0% (0/2) and NM scan 75% (3/4) sensitive. MD as a cause of abdominal symptoms and gastrointestinal bleeding may be difficult to diagnose due to nonspecific presentations and nonspecific findings. Most prospectively diagnosed MD are on NM scan in patients with GI bleed with abdominal pain (sensitivity of >70%). CT is relatively insensitive for MD in all symptomatology groups (0 to 29%). •Most children with symptomatic Meckel diverticulum present with nonspecific symptoms and without gastrointestinal bleeding.•Computed tomography is insensitive for the prospective imaging diagnosis of a Meckel diverticulum, even when symptomatic.•In the absence of surgery or visible cause, a Meckel's should be in the differential for pediatric small bowel obstruction.•Nuclear medicine Meckel scans are positive when the Meckel diverticulum contains gastric mucosa.
doi_str_mv 10.1016/j.clinimag.2022.07.008
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A 28-year retrospective review was performed of children under 18 years of age with MD listed as a diagnosis on pathology and/or surgical reports. The medical record was reviewed to determine presenting clinical scenarios. All imaging performed for each case was reviewed. Seventy-six patients met inclusion criteria. Of the surgically removed MD, most presented with abdominal symptoms (n = 31, 41%); gastrointestinal (GI) bleeding (n = 15, 20%), or both abdominal symptoms and GI bleeding (n = 7, 9%). Twenty-nine percent of MD were discovered incidentally at surgery performed for other reasons. Of the symptomatic MD, only 31% were prospectively diagnosed. For patients with abdominal symptoms, CT had a sensitivity of 13% (3/24) while nuclear medicine (NM) scan had a sensitivity of 0% (0/2). For patients with GI bleed, CT had a sensitivity of 29% (2/7) and NM scan had a sensitivity of 71% (10/14). For patients with both abdominal symptoms and GI bleed, CT was 0% (0/2) and NM scan 75% (3/4) sensitive. MD as a cause of abdominal symptoms and gastrointestinal bleeding may be difficult to diagnose due to nonspecific presentations and nonspecific findings. Most prospectively diagnosed MD are on NM scan in patients with GI bleed with abdominal pain (sensitivity of &gt;70%). CT is relatively insensitive for MD in all symptomatology groups (0 to 29%). •Most children with symptomatic Meckel diverticulum present with nonspecific symptoms and without gastrointestinal bleeding.•Computed tomography is insensitive for the prospective imaging diagnosis of a Meckel diverticulum, even when symptomatic.•In the absence of surgery or visible cause, a Meckel's should be in the differential for pediatric small bowel obstruction.•Nuclear medicine Meckel scans are positive when the Meckel diverticulum contains gastric mucosa.</description><identifier>ISSN: 0899-7071</identifier><identifier>EISSN: 1873-4499</identifier><identifier>DOI: 10.1016/j.clinimag.2022.07.008</identifier><language>eng</language><publisher>Philadelphia: Elsevier Inc</publisher><subject>Abdomen ; Age ; Asymptomatic ; Autopsies ; Bleeding ; Computed tomography ; Diagnosis ; Diverticulum ; Gastrointestinal bleeding ; Intestinal obstruction ; Meckel diverticulum ; Medical imaging ; Medical records ; Nuclear medicine ; Pain ; Pain sensitivity ; Pathology ; Patients ; Pediatrics ; Population ; Scintigraphy ; Small bowel obstruction ; Small intestine ; Surgery</subject><ispartof>Clinical imaging, 2022-11, Vol.91, p.37-44</ispartof><rights>2022 Elsevier Inc.</rights><rights>2022. 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A 28-year retrospective review was performed of children under 18 years of age with MD listed as a diagnosis on pathology and/or surgical reports. The medical record was reviewed to determine presenting clinical scenarios. All imaging performed for each case was reviewed. Seventy-six patients met inclusion criteria. Of the surgically removed MD, most presented with abdominal symptoms (n = 31, 41%); gastrointestinal (GI) bleeding (n = 15, 20%), or both abdominal symptoms and GI bleeding (n = 7, 9%). Twenty-nine percent of MD were discovered incidentally at surgery performed for other reasons. Of the symptomatic MD, only 31% were prospectively diagnosed. For patients with abdominal symptoms, CT had a sensitivity of 13% (3/24) while nuclear medicine (NM) scan had a sensitivity of 0% (0/2). For patients with GI bleed, CT had a sensitivity of 29% (2/7) and NM scan had a sensitivity of 71% (10/14). 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CT is relatively insensitive for MD in all symptomatology groups (0 to 29%). •Most children with symptomatic Meckel diverticulum present with nonspecific symptoms and without gastrointestinal bleeding.•Computed tomography is insensitive for the prospective imaging diagnosis of a Meckel diverticulum, even when symptomatic.•In the absence of surgery or visible cause, a Meckel's should be in the differential for pediatric small bowel obstruction.•Nuclear medicine Meckel scans are positive when the Meckel diverticulum contains gastric mucosa.</description><subject>Abdomen</subject><subject>Age</subject><subject>Asymptomatic</subject><subject>Autopsies</subject><subject>Bleeding</subject><subject>Computed tomography</subject><subject>Diagnosis</subject><subject>Diverticulum</subject><subject>Gastrointestinal bleeding</subject><subject>Intestinal obstruction</subject><subject>Meckel diverticulum</subject><subject>Medical imaging</subject><subject>Medical records</subject><subject>Nuclear medicine</subject><subject>Pain</subject><subject>Pain sensitivity</subject><subject>Pathology</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Population</subject><subject>Scintigraphy</subject><subject>Small bowel obstruction</subject><subject>Small intestine</subject><subject>Surgery</subject><issn>0899-7071</issn><issn>1873-4499</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNqFUU1P3DAQtVCR2G77FypLXHpJ8Ec2tjlRISiVqMoBzpbXmWy9zdqpnSDx75l06aWXnsYevfdm5j1CPnFWc8bbi33thxDDwe1qwYSomaoZ0ydkxbWSVdMY846smDamUkzxM_K-lD1DomnUirx8B_8LBtqFZ8hT8PMwH2iIdPoJdIQuuCkHT8c0zoObQoqX9AErxImOGQrWP13qYofw3Kd8cNEDTT1dFgpxt4iNOZUR_IQzcJDbxVRC-UBOezcU-PhW1-Tp9ubx-q66__H12_WX-8pLJqfKCSVNj8-21bLZMM71duta7ZxkoJQxfmMM4K8DrlveydY1m77pHBd823kv1-TzURe3-D1DmewhFA_D4CKkuVihWKNbw1B-Tc7_ge7TnCNuhyghGy24WFDtEeXxrJKht2PGY_OL5cwuidi9_ZuIXRKxTFlMBIlXRyLguc8Bsi0erfRoc0Z3bJfC_yReAamXmf8</recordid><startdate>202211</startdate><enddate>202211</enddate><creator>McDonald, Jennifer S.</creator><creator>Horst, Kelly K.</creator><creator>Thacker, Paul G.</creator><creator>Thomas, Kristen B.</creator><creator>Klinkner, Denise B.</creator><creator>Kolbe, Amy B.</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>202211</creationdate><title>Meckel diverticulum in the pediatric population: Patient presentation and performance of imaging in prospective diagnosis</title><author>McDonald, Jennifer S. ; 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subjects Abdomen
Age
Asymptomatic
Autopsies
Bleeding
Computed tomography
Diagnosis
Diverticulum
Gastrointestinal bleeding
Intestinal obstruction
Meckel diverticulum
Medical imaging
Medical records
Nuclear medicine
Pain
Pain sensitivity
Pathology
Patients
Pediatrics
Population
Scintigraphy
Small bowel obstruction
Small intestine
Surgery
title Meckel diverticulum in the pediatric population: Patient presentation and performance of imaging in prospective diagnosis
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