Interference-resistant aptasensor with tetrahedral DNA nanostructure for profenofos detection based on the composites of graphene oxide and polyaniline

•A gold-tetrahedral DNA nanostructure (Au-TDN) was independently designed.•Au-TDN can make its aptamers keep in a highly ordered vertical direction.•Au-TDN could improve the binding efficiency of aptamer and target pesticide.•GO@PANI was prepared using graphene oxide (GO) and polyaniline (PANI). In...

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