Discovery of Novel cccDNA Reducers toward the Cure of Hepatitis B Virus Infection

Chronic hepatitis B virus (HBV) infection is a worldwide disease that causes thousands of deaths per year. Currently, there is no therapeutic that can completely cure already infected HBV patients due to the inability of humans to eliminate covalently closed circular DNA (cccDNA), which serves as th...

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Veröffentlicht in:	Journal of medicinal chemistry 2022-08, Vol.65 (16), p.10938-10955
Hauptverfasser:	Chen, Dongdong, Tan, Xuefei, Chen, Wenming, Liu, Yongfu, Li, Chao, Wu, Jun, Zheng, Jiamin, Shen, Hong C., Zhang, Meifang, Wu, Waikwong, Wang, Lin, Xiong, Jing, Dai, Jieyu, Sun, Kai, Zhang, Jitao David, Xiang, Kunlun, Li, Baocun, Ni, XiaoJu, Zhu, Qihui, Gao, Lu, Wang, Li, Feng, Song
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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